Results 161 to 170 of about 1,275,682 (317)

Moral Hazard and the Composition of Transfers: Theory with an Application to Foreign Aid [PDF]

The paper presents a theoretical and empirical analysis of a donor’s choice of the composition of unrestricted and in-kind/restricted transfers to a recipient and how this composition is adjusted in response to changes in the moral hazard behavior of the
Amegashie, J. Atsu, Ouattara, Bazoumanna, Strobl, Eric   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Effect of Donor-recipient Size on Graft Growth in Pediatric Donor-to-pediatric Recipient Kidney Transplantation. [PDF]

Transplant Direct
Wang J, Wang C, Zhang Z, Hao M, Sun Y, Chen R, Liu F, Zhai Y, Xu H, Shen Q.   +9 more
europepmc   +1 more source

Utility versus Income-Based Altruism [PDF]

In Dictator Game experiments where the information status of the participants varies we find that a certain type of proposer tends to reduce his offers when the recipient has incomplete information about the pie size.
Bolle, Friedel, Kritikos, Alexander S.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A Practical Algorithm for Donor- and Recipient-site Selection in Vascularized Lymph Node Transfer in Extremity Lymphedema. [PDF]

Plast Reconstr Surg Glob Open
Kappos EA, Fabi A, Müller VA, Wendelspiess SR, Haas Y, Stoffel J, Halbeisen FS, Müller BP, Kettelhack C, Schaefer DJ, Vasselli B, Aufmesser-Freyhardt B, Meier H, Franke C, Andree C, Seidenstuecker K.   +15 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Deceased kidney donor cystatin C and subsequent recipient measured glomerular filtration rate at one year after transplantation. [PDF]

PLoS One
Dielwart IJC, Kremer D, Knobbe TJ, Groothof D, Leuvenink HGD, Kootstra-Ros JE, de Borst MH, van Londen M, Sanders JF, Pol RA, Bakker SJL, TransplantLines investigators.   +11 more
europepmc   +1 more source

Ecotoxicology and Biogeochemical Functioning of Bleached Pulp Mill Recipient and Non-recipient Lake Sediments [PDF]

, 1999
Suominen, Kimmo
core