Results 71 to 80 of about 1,345,957 (289)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Saturated Gain-Induced Non-Reciprocal Transmission and Broadband On-Chip Optical Isolator
PhotonicsTo overcome the limitation of dynamic reciprocity, a new method for designing broadband on-chip optical isolators is proposed and demonstrated based on saturated gain, which is able to support simplex and duplex operation modes. By connecting a saturated
Mingyuan Xue +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
PENERAPAN PEMBELAJARAN TIMBAL BALIK (Reciprocal teaching) \ud DALAM UPAYA MENINGKATKAN PRESTASI BELAJAR dan AKTIVITAS \ud SISWA PADA PEMBELAJARAN BIOLOGIDI SMAN 2 BATU [PDF]
, 2009 Reciprocal study ( Reciprocal Teaching) is an strategy procedure designed to teach to student about cognate strategys and also to assist student to comprehend reading better, by using approach ( Reciprocal Teaching) student taught by four understanding ...
MULYANA, SUCI
core
Reconfigurable optomechanical circulator and directional amplifier
, 2017 Non-reciprocal devices, which allow the non-reciprocal signal routing, serve as the fundamental elements in photonic and microwave circuits and are crucial in both classical and quantum information processing.
Chen, Yuan +7 more
core +2 more sources
Reciprocity: a fragile equilibrium [PDF]
Netherlands Journal of Legal Philosophy, 2014 Reciprocity: a fragile equilibrium Reciprocity may serve to explain or to justify law. In its latter capacity, which is the topic of this article, reciprocity is commonly turned into a highly idealized notion, as either a balance between two free and equal parties or as the possibility of communication tout court.
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A New Lower Bound for the Distinct Distance Constant
, 2015 The reciprocal sum of Zhang sequence is not equal to the Distinct Distance Constant. This note introduces a $B_2$-sequence with larger reciprocal sum, and provides a more precise estimation of the reciprocal sums of Mian-Chowla sequence and Zhang ...
Salvia, Raffaele
core
Non-crossing frameworks with non-crossing reciprocals
, 2003 We study non-crossing frameworks in the plane for which the classical reciprocal on the dual graph is also non-crossing. We give a complete description of the self-stresses on non-crossing frameworks whose reciprocals are non-crossing, in terms of: the ...
Orden, David +5 more
core +3 more sources
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source