Results 81 to 90 of about 482,932 (313)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Experimental Economics, 2009 AbstractUsing combined experimental and survey data, this paper provides empirical evidence that firm productivity is related to worker's pro-social behavior in the workplace. At the firm level, we find a strong positive relationship between firm productivity and reciprocating behavior among workers. Investigating workers’ individual behavior we find a
Barr, Abigail, Serneels, Pieter
openaire +4 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Reciprocal Chains: Foundations [PDF]
, 2020 Reciprocal processes are stochastic processes such that the current state only depends on the nearest past and future. The research on continuous-time reciprocal processes has been comprehensive since the 1970s, while surprisingly discrete-time ...
Saize, Stefane, +2 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Applying local context to design and implement patient room whiteboards
BMJ Open Quality, 2021 Jennifer Yoon +8 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Reciprocal Net project will construct and deploy a distributed, open, extensible digital collection of molecular structures. Associated with the collection will be software tools for visualizing, interacting with, and rendering printable images of ...
Huffman, John
core
Ultimate and proximate mechanisms of reciprocal altruism in rats [PDF]
, 2016 The reciprocal exchange of goods and services among social partners is a conundrum in evolutionary biology because of its proneness to cheating, but also the behavioral and cognitive mechanisms involved in such mutual cooperation are hotly debated ...
Rutte, Claudia +2 more
core +1 more source
To reciprocate or not to reciprocate: Exploring temporal qualities in reciprocal exchanges in networks [PDF]
, 2014 In this article, we sought to draw theoretical explanations of reciprocal exchanges in networks and how reciprocity is seen as the building block of network sustainability through employing a temporal perspective. The article’s main contribution was to provide fresh insights into how temporality, drawn upon Bergson’s philosophy, advanced the way we ...
Abualqumboz, M, Chan, PW
openaire