Results 41 to 50 of about 433,847 (219)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Revista Iberoamericana de Estudios de Desarrollo, 2021 In the context of the current systemic crisis, neoliberal capitalism is widely questioned for its unsustainability, but there is a lack of proposals from other epistemological and ontological frameworks that allow the construction of real alternatives of
Patricia Viera-Bravo
doaj +1 more source
, 2016 The paper introduces the notions of an elliptic pair, an elliptic cycle and an elliptic list over a square free positive integer d. These concepts are related to the notions of amicable pairs of primes and aliquot cycles that were introduced by Silverman
Babinkostova, Liljana +4 more
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Enabling consumer reciprocity through voucher campaigns [PDF]
REGE Revista de GestãoPurpose – This study proposes that reciprocity appeal may influence consumers helping behavior. The authors suggest that this influence depends on the target of reciprocity (direct vs. indirect), consumer–brand social distance (close vs.
Juliano Domingues da Silva +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
The Evolution of Cooperation and Diversity under Integrated Indirect Reciprocity
GamesIndirect reciprocity is one of the major mechanisms driving the evolution of cooperation in human societies. There are two types of indirect reciprocity: upstream and downstream reciprocity.
Tatsuya Sasaki +3 more
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ECONOMY OF RECIPROCITY: THE WELL-FORGOTTEN NEW
Вестник Российского экономического университета имени Г. В. Плеханова, 2017 The article investigates present day trends of joint consumption economy or economy of reciprocity from the point of view of institutional and economic theory.
Irina P. Komarova +2 more
doaj +1 more source