Results 61 to 70 of about 317,231 (261)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Enhanced Recognition Memory in Grapheme-Colour Synaesthesia for Different Categories of Visual Stimuli

Frontiers in Psychology, 2013
Memory has been shown to be enhanced in grapheme-colour synaesthesia, and this enhancement extends to certain visual stimuli (that don’t induce synaesthesia) as well as stimuli comprised of graphemes (which do).
Jamie eWard, Peter eHovard, Alicia eJones, Nicolas eRothen   +3 more
doaj   +1 more source

Recognition memory and reaction time

Acta Psychologica, 1967
Abstract Sternberg has proposed that recognition memory involves a serial and exhaustive search process. It is presumed that a representation of the test stimulus is successively compared to representations of every item in a to-be-remembered set. One prediction from the theory is that reaction time to a stimulus probe should not be a function of the
R E, Morin, D V, Derosa, V, Stultz
openaire   +2 more sources

Recognition Memory for Faces and Scenes [PDF]

The Journal of General Psychology, 2013
Previous studies have suggested that face memory is unique; however, evidence is inconclusive. To further explore this issue, we investigated recognition memory for unfamiliar faces and scenes. Participants (n = 123) intentionally memorized the stimuli and then engaged in recognition tests. Recognition was measured following short (20 minutes) and long
Sato, Wataru, Yoshikawa, Sakiko
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The Development of Attention Systems and Working Memory in Infancy

Frontiers in Systems Neuroscience, 2016
In this paper, we review research and theory on the development of attention and working memory in infancy using a developmental cognitive neuroscience framework.
Greg D. Reynolds, Alexandra C. Romano
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Effects of multisensory study on long-term memory for pictures and sounds

Acta Psychologica
Studies have provided some evidence for a benefit of congruent multisensory study format on short-term recognition memory for pictures and sounds, even when the secondary modality is task-irrelevant.
Christian Georgiev, René Zeelenberg, Diane Pecher   +2 more
doaj   +1 more source

The role of the hippocampus in recognition memory [PDF]

Cortex, 2017
Many theories of declarative memory propose that it is supported by partially separable processes underpinned by different brain structures. The hippocampus plays a critical role in binding together item and contextual information together and processing the relationships between individual items.
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source