Results 61 to 70 of about 348,442 (309)

Hippocampal involvement in glucose facilitation of recognition memory: Event-related potential components in a dual-task paradigm [PDF]

open access: yes, 2015
Background - Glucose administration may facilitate hippocampus-mediated recognition memory (‘remember’ rather than familiarity ‘know’ responses). Objective - This study aimed to investigate the electrophysiological correlates of this phenomenon in a ...
Riby, Leigh   +13 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Perceptual functions of perirhinal cortex in rats: zero-delay object recognition and simultaneous oddity discriminations [PDF]

open access: yes, 2007
The perirhinal cortex (PRh) is widely accepted as having an important role in object recognition memory in humans and animals. Contrary to claims that PRh mediates declarative memory exclusively, previous evidence suggests that PRh has a role in the ...
Bussey, Timothy J.   +4 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Animacy and threat in recognition memory [PDF]

open access: yesMemory & Cognition, 2020
Animate items are better remembered than inanimate items, suggesting that human memory has evolved to prioritize information related to survival. The proximate mechanisms for the animacy effect are not yet known, but one possibility is that animate items are more likely to capture attention, which then leads to better memory for those items.
openaire   +3 more sources

Effects of Iconicity in Recognition Memory

open access: yesCognitive Science, 2023
AbstractIconicity refers to a resemblance between word form and meaning. Previous work has shown that iconic words are learned earlier and processed faster. Here, we examined whether iconic words are recognized better on a recognition memory task. We also manipulated the level at which items were encoded—with a focus on either their meaning or their ...
Sidhu, David M.   +2 more
openaire   +3 more sources

Age-related increases in false recognition: The role of perceptual and conceptual similarity [PDF]

open access: yes, 2014
Older adults are more likely to falsely recognize novel events than young adults, and recent behavioral and neuroimaging evidence points to a reduced ability to distinguish overlapping information due to decline in hippocampal pattern separation. However,
Morcom, Alexa   +9 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Theta and gamma oscillations in the rat hippocampus support the discrimination of object displacement in a recognition memory task

open access: yesFrontiers in Behavioral Neuroscience, 2022
Episodic memory depends on the recollection of spatial and temporal aspects of past experiences in which the hippocampus plays a critical role. Studies on hippocampal lesions in rodents have shown that dentate gyrus (DG) and CA3 are necessary to detect ...
Lívia Neves   +16 more
doaj   +1 more source

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