Results 81 to 90 of about 28,362 (259)

Mining user behavior patterns based on reinforcement learning algorithm to optimize service robot interaction strategy

open access: yesMechanics & Industry
In order to resolve the challenges of reduced adaptability and generalization stemming from complicated user behavior and sparse feedback in service robot interactions, this paper presents a reinforcement learning-based approach to user behavior pattern ...
Guo Min, Feng Zhen
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

The Effect of Rewards and Green Human Resource Management on Employee Turnover at the Sukoharjo District Land Office

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study explores the influence of rewards and Green Human Resource Management (GHRM) practices on employee turnover at the Sukoharjo District Land Office, with job satisfaction as a mediating variable.
Mohamad Izza Fathan, Imronudin Imronudin
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

YUFE Recognition and Reward System

open access: yes
YUFE (Young Universities for the Future of Europe) is a European university alliance that bring together ten universities across Europes. According to its vision and mission, the objective of YUFE is to be a front-running European university alliance that shapes a holistic and inclusive future for European learners and the needs of society. YUFE brings
Kekäle, Jouni   +2 more
openaire   +4 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

What drives performance in zakat institutions? Examining affiliation needs and non-financial compensation at BAZNAS South Lampung

open access: yesAsian Journal of Islamic Management
Purpose – This research investigates the primary drivers influencing the performance of the national amil zakat agency (Badan amil zakat nasional amil, BAZNAS) in South Lampung, specifically addressing the issue of unfulfilled zakat collection targets.
Zaenal Arifin   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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