Results 131 to 140 of about 1,379,490 (255)

Affinity of recombinant antibody and antibody fragment binding to human thyroglobulin: potential applications in gene therapy

, 1998
International audienceRecombinant antibodies and antibody fragments are currently being produced. They can be used in vitro for the structural study of antigen-antibody interactions for instance, but their in vivo production may have applications for ...
Mani, J. C., Marin, M., Biard-Piechaczyk, M., Noel, D., Pau, B., Navarro-Teulon, I., Piechaczyk, Marc, Påhlsson, Peter,, Fassina G, Ye, Lei,, Cassani G, Rauffer-Bruyère, Nathalie, Altschuh, Danièle, Larsson, Per-Olof,, De Falco S, Gustavsson, Per-Erik,, Richalet-Secordel, Pascale, Palombo G, Ramström, Olof,, Axelsson, Anders,, Christensen, Lars, Regenmortel, Marc H. V. Van, Chatellier, Jean, Zeder-Lutz, Gabrielle, Tortora M, Mosbach, Klaus,, Lundblad, Arne,, Witz, Jean, Månsson, Mats Olle,, Ohlson, Sten,, Liljeblad, Mathias,, Lund University.   +31 more
core   +1 more source

Editorial: Recent Advances in Recombinant Antibody Therapeutics and Diagnostics for Infectious Diseases. [PDF]

Front Public Health, 2022
Lim TS, Hust M, Visai L.
europepmc   +1 more source

An Antimicrobial, Cell‐Adhesive, and Growth Factor‐Producing Living Material Engineered From Bacillus subtilis Biofilms for Wound Healing

Advanced Healthcare Materials, EarlyView.
Bacillus subtilis is engineered to produce cell‐adhesive biofilms by functionalization of its biofilm scaffold protein TasA with a cell‐adhesion sequence. Living bacteria within the biofilm are also engineered to secrete growth factors and natively produce antimicrobial peptides (AMPs), resulting in a cell‐adhesive, antimicrobial, and growth factor ...
Mélanie Côté‐Cyr, Marie‐Jeanne Archambault, Caroline Dupuis, Steve Bourgault   +3 more
wiley   +1 more source

Designing and Optimizing of Multiplex Polymerase Chain Reaction for Amplification of Human Anti-Tetanus Toxoid Antibody Genes

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2014
Background and Objectives: Antibodies are used in many areas of diagnosis and treatment. Fully human monoclonal antibodies (mAb) have attracted high attention due to not stimulating immune response in the body. This study was carried out with the purpose
masoumeh Bazzaz, Hamideh Rouhaninejad, Ramin Fallahzadeh, Seyed Hamid Reza Khatami, Jalil Fallah Mehrabadi   +4 more
doaj  

Optimization of recombinant antibody production based on the vector design and the level of metabolites for generation of Ig- producing stable cell lines. [PDF]

J Genet Eng Biotechnol, 2023
Toporova VA, Argentova VV, Aliev TK, Panina AA, Dolgikh DA, Kirpichnikov MP.   +5 more
europepmc   +1 more source

The Role of Viscoelasticity in Heterogeneous Glioblastoma Stem Cell Invasion in Biomimetic 3‐Dimensional Hydrogels

Advanced Healthcare Materials, EarlyView.
The role of viscoelasticity in the invasion of heterogeneous glioblastoma stem cells (GSCs) was investigated with GSCs categorized into subgroups based on molecular profile, as Reactive, Invasive, or Constructive using viscoelastic biomimetic hyaluronan‐oxime hydrogels.
Nicole J. Blaine, Arianna Skirzynska, Allysia A. Chin, Julie Audet, Molly S. Shoichet   +4 more
wiley   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Augmenting recombinant antibody production in HEK293E cells: optimizing transfection and culture parameters. [PDF]

Antib Ther, 2022
Heng ZS, Yeo JY, Koh DW, Gan SK, Ling WL.   +4 more
europepmc   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Effectiveness of a Bivalent Recombinant Vaccine on the Production of Neutralizing Antibodies Against BoNT/C, BoNT/D, BoNT/CD e BoNT/DC in Bovines

Vaccines
Background/Objectives. Bovine botulism, although relatively rare, presents significant economic losses due to high mortality rates and restrictions on livestock product trade.
Ilenia Drigo, Luca Zandonà, Elena Tonon, Katia Capello, Luca Bano   +4 more
doaj   +1 more source