Results 181 to 190 of about 4,269,972 (308)

Molecular characterization and recombinant expression of Babesia ovis SBP4 protein as a potential serodiagnostic antigen. [PDF]

Sci Rep
Ozubek S, Keskin S, Ulucesme MC, Eyvaz A, Alatas M, Doymaz MZ, Aktas M.   +6 more
europepmc   +1 more source

CysPresso: a classification model utilizing deep learning protein representations to predict recombinant expression of cysteine-dense peptides. [PDF]

BMC Bioinformatics, 2023
Ouellet S, Ferguson L, Lau AZ, Lim TKY.
europepmc   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Recombinant Expression and Antimicrobial Mechanism of Cysteine-Rich Antimicrobial Peptides from <i>Tigriopus japonicus</i> Genome. [PDF]

Mar Drugs
Pu D, Tao H, Pang J, Shi H, Wang J, Zhang W.   +5 more
europepmc   +1 more source

Rational domestication of a plant-based recombinant expression system expands its biosynthetic range. [PDF]

J Exp Bot, 2022
Jackson MA, Chan LY, Harding MD, Craik DJ, Gilding EK.   +4 more
europepmc   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Recombinant expression and immunogenicity verification of Dabie bandavirus proteins Gn and Gc. [PDF]

Front Microbiol
Lou X, Mao H, Lou Y, Sun Y, Wang F, Wang M, Zhang L, Fang Z, Yan H, Zhang H.   +9 more
europepmc   +1 more source

Recombinant Expression in Pichia pastoris System of Three Potent Kv1.3 Channel Blockers: Vm24, Anuroctoxin, and Ts6. [PDF]

J Fungi (Basel), 2022
Borrego J, Naseem MU, Sehgal ANA, Panda LR, Shakeel K, Gaspar A, Nagy C, Varga Z, Panyi G.   +8 more
europepmc   +1 more source

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

Advanced Science, EarlyView.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

Impact of recombinant expression in <i>Komagataella phaffii</i> on the allergenic properties of the peanut allergen Ara h 2. [PDF]

Front Immunol
Wangorsch A, Jamin A, Wolfheimer S, Albrecht M, Vieths S, Lidholm J, Scheurer S.   +6 more
europepmc   +1 more source