Results 111 to 120 of about 952,798 (315)
Frontiers in Plant SciencePlant microRNAs (miRNAs) are small non-coding RNA molecules that usually negatively regulate gene expression at the post-transcriptional level. Recent data reveal that plant miRNAs are not limited to individual plants but can transfer across different ...
Lei Shi +7 more
doaj +1 more source
Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro [PDF]
, 2007 Prion diseases, or transmissible spongiform encephalopathies (TSEs) are typically characterised by CNS accumulation of PrPSc, an aberrant conformer of a normal cellular protein PrPC.
Oxley, David +9 more
core +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Вавиловский журнал генетики и селекции, 2018 The present work describes the construction of the gene encoding the recombinant protein flagGprotE, its synthesis, purification and study. The recombinant flagGprotE protein is a promising molecule for developing a candidate recombinant vaccine ...
P. A. Belavin +4 more
doaj +1 more source
Recombinant protein polymers in biomaterials
Frontiers in Bioscience, 2013 Naturally occurring protein-based materials have been found that function as critical components in biomechanical response, fibers and adhesives. A relatively small but growing number of recombinant protein-based materials that mimic the desired features of their natural sources, such as collagens, elastins and silks, are considered as an alternative ...
openaire +2 more sources
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
One Step ahead in Cell Cultivation – International Advanced Training Course at ZHAW Waedenswil
CHIMIA, 2015 At ZHAW Waedenswil, students from all over the world meet to gain an insight into the laboratories and learn the latest processes in cell cultivation to produce drugs, vaccines and cosmetics.
Elsbeth Heinzelmann
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Expression Status of UBE2Q2 in Colorectal Primary Tumors and Cell Lines
Iranian Journal of Medical Sciences, 2014 Background: Activation of the ubiquitin-proteasome pathway in various malignancies, including colorectal cancer, is established. This pathway mediates the degradation of damaged proteins and regulates growth and stress response.
Sayed Mohammad Shafiee +6 more
doaj
Vaccination contre la souche influenza PR8 à l'aide d'un vaccin recombinant SG33-M2e [PDF]
, 2010 Cette étude présente un essai d’immunisation à l’aide d’un vaccin recombinant poxviral. Le processus de fabrication du vaccin est basé sur la fusion protéique entre l’antigène considéré et une protéine d’enveloppe du poxvirus.
Boyer, Guillaume
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