Results 221 to 230 of about 6,805,202 (337)

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee, Peter Lialios, Micaila Curtis, James Williams IV, Yoontae Kim, Paul Salipante, Steven Hudson, Mandy B. Esch, Moshe Levi, Joanna Kitlinska, Stella Alimperti   +10 more
wiley   +1 more source

Role of Recombinant Proteins for Treating Rheumatoid Arthritis. [PDF]

Avicenna J Med Biotechnol
Soleimani Sasani M, Moradi Y.
europepmc   +1 more source

Avidity-Based Method for the Efficient Generation of Monoubiquitinated Recombinant Proteins. [PDF]

J Am Chem Soc, 2023
Nelson SL, Li Y, Chen Y, Deshmukh L.
europepmc   +1 more source

Inhibition of activated protein C by recombinant alpha 1-antitrypsin variants with substitution of arginine or leucine for methionine358.

, 1990
Mary J. Heeb, Rainer Bischoff, Michael Courtney, John H. Griffin   +3 more
openalex   +1 more source

Protein kinase C group B members PKC-δ, -ɛ, -ζ and PKC-L(η). Comparison of properties of recombinant proteins in vitro and in vivo [PDF]

, 1992
Marek Liyanage, David Frith, Etta Livneh, Silvia Stabel   +3 more
openalex   +1 more source

Co‐Delivery of Multiple Toll‐Like Receptor Agonists and Avian Influenza Hemagglutinin on Protein Nanoparticles Enhances Vaccine Immunogenicity and Efficacy

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
This research highlights a novel application of protein nanoparticles to effectively modulate the strength, breadth, and bias of an immune response against influenza virus. Nanoparticles precisely co‐delivering antigen (H5) and multiple adjuvants (CpG and FliCc) present a way to improve and direct prophylactic immune responses which can be applicable ...
Aaron Ramirez, Jenny E. Hernandez‐Davies, Aarti Jain, Lu Wang, Erwin Strahsburger, D. Huw Davies, Szu‐Wen Wang   +6 more
wiley   +1 more source

Use of recombinant proteins for the diagnosis and prevention of Mycoplasma bovis: a systematic review. [PDF]

Front Vet Sci
Gomes CP, da Silva LSC, Santos Júnior MN, Barbosa MS, Neves WS, Ribeiro VG, Bastos BL, Marques LM.   +7 more
europepmc   +1 more source

A Convenient Self-Removing Affinity Tag Method for the Simple Purification of Tagless Recombinant Proteins. [PDF]

Curr Protoc, 2023
Prabhala SV, Mayone SA, Moody NM, Kanu CB, Wood DW.   +4 more
europepmc   +1 more source

Matrix Viscoelasticity Orchestrates Osteogenesis via Mechanotransduction Mediated Metabolic Switch in Macrophages

Advanced Healthcare Materials, Volume 14, Issue 11, April 25, 2025.
Fast‐relaxation viscoelastic hydrogel triggers a metabolic shift in macrophages, favoring oxidative phosphorylation (OXPHOS) over glycolysis via vasodilator‐stimulated phosphoprotein (VASP) / hypoxia‐inducible factor 1 alpha (HIF1α) signaling meditated mechanotransdution, thereby enhancing their capacity to recruit mesenchymal stem cells (MSCs) and ...
Dihao Tao, Hanzhe Wang, Shiping Chang, Jiayu Cheng, Ningning Da, Li Zhang, Jianhua Yang, Wenzhe Wang, Feng Xu, Bei Li   +9 more
wiley   +1 more source

Anti-stroke biologics: from recombinant proteins to stem cells and organoids. [PDF]

Stroke Vasc Neurol
Miao ZW, Wang Z, Zheng SL, Wang SN, Miao CY.   +4 more
europepmc   +1 more source