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Single-cycle parainfluenza virus type 5 vectors for producing recombinant proteins, including a humanized anti-V5 tag antibody. [PDF]

open access: yesJ Gen Virol
Randall RE   +8 more
europepmc   +1 more source
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Recombination genes and proteins

Current Opinion in Genetics & Development, 1994
The recombination of DNA takes place by a multistep process involving numerous gene products. In the past year, studies using bacterial proteins have led to a number of significant advances in our understanding of the enzymes of recombination and of the reactions that they catalyze.
H J, Dunderdale, S C, West
openaire   +2 more sources

Recombination Proteins in Yeast

Annual Review of Genetics, 2004
▪ Abstract  The process of homologous recombination promotes error-free repair of double-strand breaks and is essential for meiosis. Central to the process of homologous recombination are the RAD52 group genes (RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2), most of which were identified by their requirement for the ...
Berit Olsen, Krogh   +1 more
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Recombinant Protein Production in Yeasts

Molecular Biotechnology, 2005
Recombinant DNA (rDNA) technologies (genetic, protein, and metabolic engineering) allow the production of a wide range of peptides, proteins, and biochemicals from naturally nonproducing cells. These technologies, now approx 25 yr old, have become one of the most important technologies developed in the twentieth century.
PORRO, DANILO   +3 more
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Recombinant proteins for therapy

Trends in Pharmacological Sciences, 1996
Recombinant therapeutic proteins have become increasingly important over the past ten years. Numerous products derived from 20 different proteins are already on the market. In this review Peter Buckel discusses the issues surrounding the use of recombinant proteins as therapeutic agents.
openaire   +2 more sources

Recombinant Protein Production in Yeasts

2004
Recombinant DNA (rDNA) technologies (genetic, protein, and metabolic engineering) allow the production of a wide range of peptides, proteins, and biochemicals from naturally nonproducing cells. This technology, now approx 25 yr old, is becoming one of the most important technologies developed in the 20th century.
Porro, D, Mattanovich, D
openaire   +2 more sources

Recombinant Protein Production in Yeasts

2011
Recombinant protein production is a multibillion-dollar market. The development of a new product begins with the choice of a production host. While one single perfect host for every protein does not exist, several expression systems ranging from bacterial hosts to mammalian cells have been established.
Mattanovich, D   +5 more
openaire   +3 more sources

Insights on the Formulation of Recombinant Proteins

2019
Recombinant proteins are large and complex molecules, whose therapeutic activity highly depends on their structure. Formulation of biopharmaceuticals aims at stabilizing protein conformation, promoting its efficacy, and preventing safety concerns, such as immunogenicity. Currently, the rational design of formulations is possible due to the availability
Ribeiro, Rita   +4 more
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Preparation of Recombinant Proteins in Milk

2004
Using transgenic animals as the source of recombinant proteins has several specific advantages. Large amounts of proteins can be obtained, essentially from milk. These proteins are often properly processed. They are in a number of cases correctly folded, assembled, cleaved, glycosylated, gamma-carboxylated, and so on.
openaire   +3 more sources

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