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Overview of the Characterization of Recombinant Proteins

Current Protocols in Protein Science, 1995
AbstractThis overview provides guidelines for the characterization of recombinantly expressed proteins (e.g., verifying primary structure and appropriate post‐translational modifications), along with methodologies for characterizing the proteins according to size, X‐ray structure, absorbance, biological activity, and subunit structure.
Denslow, Nancy D.   +2 more
openaire   +3 more sources

Recombinant proteins for genetic disease

Clinical Genetics, 1999
The era of molecular biology has led to the development of powerful tools capable of generating therapeutics for genetic disorders. Although there is much current emphasis placed on the development of ‘gene therapy’ for human disease, developments in the production and availability of recombinant proteins are likely to have a more substantial impact on
C S, Russell, L A, Clarke
openaire   +2 more sources

[Recombinant protein folding and production].

Medecine sciences : M/S, 2005
The biotechnology of recombinant protein production is now entering its most advanced stage, and the growth of industrial protein pharmaceuticals provides solid proof of this evolution. However, the systematic conversion of genetic information into a biologically active protein is constantly confronted by the fundamental problem of protein folding in ...
Betton, Jean-Michel, Chaffotte, Alain
openaire   +2 more sources

SCHEMA-Guided Protein Recombination

2004
Publisher Summary This chapter examines the different aspects of SCHEMA-guided protein recombination. SCHEMA is a scoring function that predicts which elements in homologous proteins can be swapped without disturbing the integrity of the structure. Using the structural coordinates of the parent proteins, SCHEMA identifies pairs of residues that are ...
Silberg, Jonathan J.   +2 more
openaire   +3 more sources

Recombinant Proteins in Vaccine Development

2003
The outer membrane of Neisseria meningitidis contains a variety of proteins with the potential for inclusion in new meningococcal vaccines (1). Studies on the vaccine potential of these proteins would be facilitated by the production of pure recombinant protein, free from other components of the Neisseria outer membrane.
M, Christodoulides   +2 more
openaire   +2 more sources

TISIGNER.com: Web Services for Improving Recombinant Protein Production.

Nucleic Acids Research, 2021
Chun Shen Lim   +2 more
exaly  

Recombinant DNA: Hypothetical Fears vs. Potential Benefits

Ca-A Cancer Journal for Clinicians, 1977
John J Holland
exaly  

Recombinant Protein Secretion in Escherichia coli

Biotechnology Advances, 2005
Filipe J. Mergulhão   +2 more
exaly  

Production of Recombinant Proteins by Yeast Cells

Biotechnology Advances, 2012
Pınar Çalık, Eda Çelik
exaly  

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