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A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. [PDF]
Nat CommunSchönherr R +11 more
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Recombinant Therapeutic Protein Vaccines
Protein & Peptide Letters, 2013Recombinant technology has ushered in a new era for the pharmaceutical industry. Protein therapeutics, including plasma-derived products and antibodies obtained from the serum of infected patients, have been successfully adopted and utilized to treat various indications.
Satoshi, Ohtake, Tsutomu, Arakawa
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Recombination genes and proteins
Current Opinion in Genetics & Development, 1994The recombination of DNA takes place by a multistep process involving numerous gene products. In the past year, studies using bacterial proteins have led to a number of significant advances in our understanding of the enzymes of recombination and of the reactions that they catalyze.
H J, Dunderdale, S C, West
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Recombination Proteins in Yeast
Annual Review of Genetics, 2004▪ Abstract The process of homologous recombination promotes error-free repair of double-strand breaks and is essential for meiosis. Central to the process of homologous recombination are the RAD52 group genes (RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2), most of which were identified by their requirement for the ...
Berit Olsen, Krogh +1 more
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SCHEMA-Guided Protein Recombination
2004Publisher Summary This chapter examines the different aspects of SCHEMA-guided protein recombination. SCHEMA is a scoring function that predicts which elements in homologous proteins can be swapped without disturbing the integrity of the structure. Using the structural coordinates of the parent proteins, SCHEMA identifies pairs of residues that are ...
Silberg, Jonathan J. +2 more
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Recombinant Protein Production in Yeasts
Molecular Biotechnology, 2005Recombinant DNA (rDNA) technologies (genetic, protein, and metabolic engineering) allow the production of a wide range of peptides, proteins, and biochemicals from naturally nonproducing cells. These technologies, now approx 25 yr old, have become one of the most important technologies developed in the twentieth century.
PORRO, DANILO +3 more
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Recombinant proteins for therapy
Trends in Pharmacological Sciences, 1996Recombinant therapeutic proteins have become increasingly important over the past ten years. Numerous products derived from 20 different proteins are already on the market. In this review Peter Buckel discusses the issues surrounding the use of recombinant proteins as therapeutic agents.
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Recombinant Protein Production in Yeasts
2011Recombinant protein production is a multibillion-dollar market. The development of a new product begins with the choice of a production host. While one single perfect host for every protein does not exist, several expression systems ranging from bacterial hosts to mammalian cells have been established.
Mattanovich, D +5 more
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Recombinant Protein Production in Yeasts
2004Recombinant DNA (rDNA) technologies (genetic, protein, and metabolic engineering) allow the production of a wide range of peptides, proteins, and biochemicals from naturally nonproducing cells. This technology, now approx 25 yr old, is becoming one of the most important technologies developed in the 20th century.
Porro, D, Mattanovich, D
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