Results 121 to 130 of about 2,327,860 (219)

Mechanisms of tissue-type plasminogen activator (tPA) clearance by the liver

, 1992
Chemicals/CAS: mannose receptor; Mannose, 31103-86-3; PLAT protein, human; Receptors, Cell Surface; Receptors, Immunologic; Recombinant Proteins; Tissue Plasminogen Activator, EC 3.4.21 ...
Kuiper, J., Berkel T.J.C. van, Rijken, D.C., Otter, M.   +3 more
core  

Hemorrhagic transformation following tissue plasminogen activator in experimental cerebral infarction.

, 1990
The effect of an intravenous infusion of recombinant tissue plasminogen activator on hemorrhagic transformation early after middle cerebral artery territory ischemia was studied in an established awake nonhuman primate (baboon) model.
B R Copeland, W Hacke, K Anderchek, J A Koziol, G J del Zoppo   +4 more
core   +1 more source

Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress

Neural Regeneration Research
Neuroserpin, a secreted protein that belongs to the serpin superfamily of serine protease inhibitors, is highly expressed in the central nervous system and plays multiple roles in brain development and pathology.
Yumei Liao, Qinghua Zhang, Qiaoyun Shi, Peng Liu, Peiyun Zhong, Lingling Guo, Zijian Huang, Yinghui Peng, Wei Liu, Shiqing Zhang, István Adorján, Yumi Fukuzaki, Eri Kawashita, Xiao-Qi Zhang, Nan Ma, Xiaoshen Zhang, Zoltán Molnár, Lei Shi   +17 more
doaj   +1 more source

Effect of Recombinant Tissue Plasminogen Activator and 120-kHz Ultrasound on Porcine Intracranial Thrombus Density. [PDF]

Ultrasound Med Biol, 2023
Kleven RT, Huang S, Ford SM, Sakthivel K, Thomas SR, Zuccarello M, Herr AB, Holland CK.   +7 more
europepmc   +1 more source

Nebulized Recombinant Tissue Plasminogen Activator (rt-PA) for Acute COVID-19-Induced Respiratory Failure: An Exploratory Proof-of-Concept Trial. [PDF]

J Clin Med, 2023
Chowdary P, Agarwal B, Peralta MR, Bhagani S, Lee S, Goldring J, Lipman M, Waqif E, Phillips M, Philippou H, Foley JH, Mutch NJ, Ariëns RAS, Stringer KA, Ricciardi F, Watissée M, Hughes D, Nathwani A, Riddell A, Patch D, Buckley J, De Neef M, Dimber R, Diaz-Garcia C, Patel H, Nandani A, Dissanayake U, Chadwick N, Alkhatip AAAMM, Watkinson P, Raith E, Singh S, Wolff T, Jha R, Brill SE, Bakhai A, Evans A, Gilani F, Gomez K.   +38 more
europepmc   +1 more source

Interleukin 1 and lipopolysaccharide induce an inhibitor of tissue-type plasminogen activator in vivo and in cultured endothelial cells

, 1986
Human IL-1, recombinant murine IL-1 and E. coli LPS were found to be potent inducers of plasminogen activator (PA)-inhibitor activity, both in vivo, in rats, as well as in cultured human endothelial cells.
Kooistra, T., Emeis, J.J.
core  

Administration of Recombinant Tissue Plasminogen Activator for Sulcal Artery Syndrome. [PDF]

Neurol Clin Pract, 2021
Lawson EC, Hu R, Silver M, Greene JG.
europepmc   +1 more source

Role of Single Dose of Intravitreal Recombinant Tissue Plasminogen Activator in Vitreomacular Traction and Associated Macular Edema: a Retrospective Study. [PDF]

Maedica (Bucur), 2022
Sadhukhan K, Naskar S.
europepmc   +1 more source

The Utility of Automated ASPECTS in Acute Ischemic Stroke for Intravenous Recombinant Tissue Plasminogen Activator (IV-rtPA) Therapy. [PDF]

Neurol Int, 2022
Shibata S, Sakurai K, Tachikawa K, Ko R, Hino S, Fukano T, Isahaya K, Haraguchi T, Yamauchi J, Tanabe K, Nagasaka M, Hagiwara Y, Shimizu T, Akiyama H, Kobayashi Y, Hasegawa Y, Yamano Y.   +16 more
europepmc   +1 more source

Unaffected ex vivo clotting cascade by experimental hemostatic nanoparticles when introduced in the presence of recombinant tissue plasminogen activator. [PDF]

Brain Circ, 2022
Beyer M, France J, Nagaraja TN, Lavik EB, Knight RA, Lewandowski CA, Miller JB.   +6 more
europepmc   +1 more source