Results 41 to 50 of about 575,728 (172)

Immunodiagnostics of tuberculosis: 10-year experience of using immunological tests in Russia

Туберкулез и болезни лёгких, 2019
The introduction of a new generation of immunological tests based on in vitro or in vivo reactions using specific ЕSAT-6 and CFP-10 peptides allowed changing the understanding of the diagnosis of latent tuberculosis infection, as well as improving the ...
A. A. Starshinova, I. F. Dovgalyuk, P. K. Yablonskiy   +2 more
doaj   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang, Jiangbo Fan, Wenyi Liu, Di Liu, Rui Wang, Yuanyang Wang, Jianhui Sun, Huacai Zhang, Qingli Cai, Zhe Xu, Fang Xu, Jianxin Jiang, Zhen Wang, Ling Zeng   +13 more
wiley   +1 more source

New drugs and vaccines for drug-resistant Mycobacterium tuberculosis infections [PDF]

, 2008
Tuberculosis remains the most common cause of death due to a single infective organism. Despite the availability of a vaccine and chemotherapeutic options, the global disease burden remains relatively unaffected.
Willcox, Benjamin, Gurdyal S Besra, Bhatt, Apoorva; id_orcid, Dover, LG, Apoorva Bhatt, Dover, Lynn, Besra, Gurdyal; id_orcid, Besra, Gurdyal, Bhatt, Apoorva, Lynn G Dover, Bhowruth, Veemal, Veemal Bhowruth, Benjamin E Willcox   +12 more
core   +1 more source

WAYS TO OPTIMIZE DETECTION OF TUBERCULOSIS IN A PULMONOLOGY UNIT

Туберкулез и болезни лёгких, 2018
The objective: to optimize detection of tuberculosis in a pulmonology unit.Subjects and methods. In a pulmonology unit, patients suspected of having tuberculosis had a minimum number of diagnostic tests: a skin test with tuberculous recombinant allergen,
E. A. Borodulina, A. T. Inkova, B. E. Borodulin, L. V. Povalyaeva   +3 more
doaj   +1 more source

Rpf‐Toxo: A Preliminary Computationally Designed Dense Granule Antigen‐Based Multi‐Epitope Vaccine Against Toxoplasma gondii

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This graphical abstract summarizes the in silico design of the multi‐epitope vaccine candidate Rpf‐Toxo (Seq4) against Toxoplasma gondii. The workflow includes antigen selection, epitope mapping, vaccine construction, structural and immunological evaluation, toll‐like receptor‐4 docking, immune simulation, safety assessment, codon optimisation and ...
Mohamad Hosein Safari, Seyyed Amir Hosseini, Shadan Ghiabi, Shamim Ghiabi, Davood Siamian, Hamidreza Majidiani, Hamid Irannejad, Ali Asghari   +7 more
wiley   +1 more source

Update on biologic and small molecules treatments in pediatric allergic diseases

Pediatric Allergy and Immunology, Volume 37, Issue 9, September 2026.
This graphical abstract summarizes key targets, mechanisms of action, and indications of biologic and small molecules treatments in pediatric allergic diseases.abbreviations : BAS, basophil; BTK, Bruton tyrosine kinase; cDC, conventional dendritic cell; IgE, immunoglobulin E; FCER1, high affinity IgE receptor; IL, interleukin; IL4R, IL4 receptor; JAK ...
Herman T. den Dekker, Amandine Divaret Chauveau, Benoit Sterling, Stéphanie Coopman, R. Sharon Chinthrajah, Stéphanie Lejeune, Dorothea Holter, Thomas Eiwegger, Stéphanie Mallet, Mariëlle W. Pijnenburg, Antoine Deschildre   +10 more
wiley   +1 more source

EFFICIENCY OF DIASKINTEST DURING MASS PROPHYLACTIC EXAMINATIONS IN CHILDREN: PHARMACOECONOMIC ANALYSIS

Туберкулез и болезни лёгких, 2014
The efficiency of mass screenings for tuberculosis in children and adolescents was determined as a proportion of persons who were found to have tuberculosis.
N. N. Moiseeva, V. A. Aksenova, V. S. Odinets   +2 more
doaj  

Comparative Evaluation of Allergodiagnostic of Tuberculosis in Children

Эпидемиология и вакцинопрофилактика, 2016
The comparative analysis of results of the tuberculin skin test (TST) and of the skin test with the recombinant tuberculosis allergen (Diaskintest - DST) in 7978 children with active tuberculosis revealed for the first time in 2013 - 2014 was carried out.
I. V. Mikheeva, E. Yu. Burdova, A. A. Melnikova   +2 more
doaj   +1 more source

The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity

MedComm, Volume 7, Issue 7, July 2026.
Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng, Qilong Li, Ning Jiang, Qijun Chen   +3 more
wiley   +1 more source

Immunodiagnostics of tuberculosis infection in vitro in solving the issue of prescribing preventive chemotherapy

Детские инфекции (Москва), 2020
For the immunodiagnosis of tuberculosis infection, in addition to standard skin tests (Mantoux test with 2 TU PPD-L and Diaskintest), in vitro tests are currently used, one of which is the T-spot.TB test.Purpose of research. Evaluate the T-SPOT test as a
E. P. Eremenko, I. A. Sergeeva, B. E. Borodulin, E. A. Amosova   +3 more
doaj   +1 more source