Results 71 to 80 of about 575,728 (172)

Preventive Tuberculosis Services Reduces the Risk of Local Forms of Tuberculosis Development in Children on Immunosuppressive Therapy: Retrospective Cohort Study

open access: yesВопросы современной педиатрии, 2020
Background. Long-term immunosuppressive therapy in children (including genetically engineered biologic drugs, GEBD) is associated with a high risk of local tuberculosis (TB) development. Objective.
Valentina A. Aksenova   +5 more
doaj   +1 more source

Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential

open access: yesMedComm, Volume 6, Issue 11, November 2025.
This review systematically summarizes dendritic cells (DCs) originating from hematopoietic stem cells, their major subsets (cDC1s, cDC2s, pDCs, moDCs, LCs) and core functions (antigen capture/presentation, adaptive immunity activation, immune tolerance induction, and regulation of innate immune cells).
Fangfang Jin   +7 more
wiley   +1 more source

Sensitization profiles to purified plant food allergens among pediatric patients with allergy to banana. [PDF]

open access: yes, 2011
Banana fruit allergy is well known, but neither immunoglobulin E recognition patterns to purified plant food allergens nor true prevalences of putative banana allergens have been established. This study aimed to characterize β-1,3-glucanase and thaumatin-
Sánchez-Monge Laguna de Rins, Rosa   +7 more
core   +1 more source

Induration or erythema diameter not less than 5 mm as results of recombinant fusion protein ESAT6-CFP10 skin test for detecting M. tuberculosis infection

open access: yesBMC Infectious Diseases, 2020
Background Recombinant fusion protein ESAT6-CFP10 (EC) is a newly developed skin test reagent for detecting Mycobacterium tuberculosis (M. tuberculosis) infection.
Hui Zhang   +4 more
doaj   +1 more source

Design Strategies for Novel Lipid Nanoparticle for mRNA Vaccine and Therapeutics: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 6, Issue 10, October 2025.
This review summarizes strategies to optimize lipid nanoparticles (LNPs) for improved targeting, endosomal escape, and safety. It highlights mRNA design, alternative delivery systems, and recent therapeutic advances across infectious diseases, cancer, and drug applications.
Xiaochi Li   +7 more
wiley   +1 more source

Prevalence of Latent Tuberculosis Infection among Residents of Social Housing

open access: yesТуберкулез и болезни лёгких
The objective: to assess the prevalence of latent tuberculosis infection among people living in social housing.Subjects and Methods. Prevalence of latent tuberculosis infection (LTBI) was analyzed among residents of two social homes in Moscow; totally ...
E. T. Khalafova, E. M. Bogorodskaya
doaj   +1 more source

Efficiency of screening for tuberculous infection among children in Tatarstan Republic

open access: yesТуберкулез и болезни лёгких, 2016
Goal of the study: to investigate the role of skin test with tuberculous recombinant allergen (TRA) in mass screening for tuberculosis in children from high risk groups in Tatarstan Republic.Materials and methods.
R. Kh. Fatykhova, A. P. Aleks
doaj   +1 more source

EXPERIENCE OF USING RECOMBINANT ALLERGEN OF MYCOBACTERIUM TUBERCULOSIS FOR DIAGNOSTICS OF TUBERCULOUS INFECTION

open access: yesТуберкулез и болезни лёгких, 2016
117,662 children and adolescents were examined with the skin test of Diaskintest when registered for dispensary follow-up for the first time in tuberculosis control units in Orenburg Region from 2010 to 2015.
T. A. Parfenova
doaj   +1 more source

Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages. [PDF]

open access: yes, 2008
BACKGROUND: Transcriptional profiling using microarrays provides a unique opportunity to decipher host pathogen cross-talk on the global level. Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium ...
Waddell, Simon   +62 more
core   +1 more source

OPPORTUNITIES TO DIAGNOSE ACTIVE TUBERCULOSIS IN THE PATIENTS WITH CLINICALLY CURED RESPIRATORY TUBERCULOSIS

open access: yesТуберкулез и болезни лёгких, 2017
Goal of the study: to evaluate the test with tuberculous recombinant allergen (TRA) in the patients with effective treatment course due to tuberculosis, to investigate the impact of clinical, epidemiological and social factors on persistence of active ...
G. S. Balasanyants, N. S. Skotnikova
doaj   +1 more source

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