Results 21 to 30 of about 138,518 (265)

Glucomannan enhanced the macrophage activity in exposure to methicillin-resistant Staphylococcus aureus (MRSA): in-vitro study

Iranian Journal of Microbiology, 2023
Background and Objectives: The increasing number of methicillin-resistant Staphylococcus aureus persuade the need for preventive measures. Glucomannan is a polysaccharide choice for developing immunological strategies.
Melika Khanzadeh Tehrani, Mohammad Hossein Yazdi, Mohammad Reza Pourmand   +2 more
doaj   +1 more source

Recombinant vaccines

Expert Review of Vaccines, 2010
The Recombinant Vaccines: Strategies for Candidate Discovery and Vaccine Delivery conference, organized by EuroSciCon, hosted a group of UK-based and international scientists from as far afield as Malaysia and Australia. Genomic analyses of pathogens and elucidation of mechanisms of pathogenesis has advanced candidate discovery and development of ...
openaire   +5 more sources

Recombinant vaccines for COVID-19 [PDF]

Human Vaccines & Immunotherapeutics, 2020
SARS-CoV-2, the causative agent of COVID-19, has imposed a major public health threat, which needs effective therapeutics and vaccination strategies. Several potential candidate vaccines being rapidly developed are in clinical evaluation. Considering the crucial role of SARS-CoV-2 spike (S) glycoprotein in virus attachment, entry, and induction of ...
Yadav, Tushar, Srivastava, Nishant, Mishra, Gourav, Dhama, Kuldeep, Kumar, Swatantra, Puri, Bipin, Saxena, Shailendra K   +6 more
openaire   +3 more sources

Unraveling the impact of SARS-CoV-2 mutations on immunity: insights from innate immune recognition to antibody and T cell responses

Frontiers in Immunology
Throughout the COVID-19 pandemic, the emergence of new viral variants has challenged public health efforts, often evading antibody responses generated by infections and vaccinations. This immune escape has led to waves of breakthrough infections, raising
Rafael Bayarri-Olmos, Rafael Bayarri-Olmos, Adrian Sutta, Adrian Sutta, Anne Rosbjerg, Anne Rosbjerg, Mie Mandal Mortensen, Charlotte Helgstrand, Per Franklin Nielsen, Laura Pérez-Alós, Beatriz González-García, Laust Bruun Johnsen, Finn Matthiesen, Thomas Egebjerg, Cecilie Bo Hansen, Alessandro Sette, Alessandro Sette, Alba Grifoni, Ricardo da Silva Antunes, Peter Garred, Peter Garred   +20 more
doaj   +1 more source

HBs antigen and mannose loading on the surface of iron oxide nanoparticles in order to immuno-targeting: fabrication, characterization, cellular and humoral immunoassay

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Mannosylation of nanovaccine is an appropriate strategy for targeting the mannose receptors on DCs. Here, HBsAg and mannose loaded on the surface of iron oxide nanoparticles to increases HBsAg vaccine potency.
Mahsa Rezaei, Seyed Nezamedin Hosseini, Ramazan Ali Khavari-Nejad, Farhood Najafi, Mehdi Mahdavi   +4 more
doaj   +1 more source

Recombinant Vaccines: The Revolution Ahead

, 2022
The post-vaccination era has boosted constant innovations in the field of medicine and public health and has been instrumental in greatly augmenting the quality of life of human civilization. Ground-breaking scientific innovations in the twentieth and twenty-first centuries have enabled coherent vaccine design and the creation of novel vaccines for a ...
openaire   +2 more sources

Molecular insights into macrolide resistant Mycoplasma pneumoniae isolates from outpatient clinics in Tehran, Iran

Scientific Reports
The rising incidence of macrolide-resistant Mycoplasma pneumoniae (MRMP) in Asia is a significant public health concern due to its implications in severe diseases. However, limited reliable data is available on this topic from Iran.
Maryam Arfaatabar, Yasaman Sadeghi, Narjes Noori Goodarzi, Mohammad Reza Pourmand   +3 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

A Scalable Topical Vectored Vaccine Candidate against SARS-CoV-2

Vaccines, 2020
The severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) caused an ongoing unprecedented global public health crises of coronavirus disease in 2019 (CoVID-19).
Mohammed A. Rohaim, Muhammad Munir
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source