Results 61 to 70 of about 236,609 (162)

Improvement of PR8-Derived Recombinant Clade 2.3.4.4c H5N6 Vaccine Strains by Optimization of Internal Genes and H103Y Mutation of Hemagglutinin

Vaccines, 2020
Clade 2.3.4.4c H5N6 avian influenza A viruses (AIVs) may have originally adapted to infect chickens and have caused highly pathogenic avian influenza (HPAI) in poultry and human fatalities.
Se-Hee An, Seung-Min Hong, Seung-Eun Son, Jin-Ha Song, Chung-Young Lee, Jun-Gu Choi, Youn-Jeong Lee, Jei-Hyun Jeong, Jun-Beom Kim, Chang-Seon Song, Jae-Hong Kim, Kang-Seuk Choi, Hyuk-Joon Kwon   +12 more
doaj   +1 more source

Advances in the design and development of oncolytic measles viruses. [PDF]

, 2015
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian, Raffel, Corey, Studebaker, Adam W   +2 more
core   +1 more source

Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system [PDF]

, 2016
BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens.
Blake, D P, Cockle, C, Crouch, C, Macdonald, S E, Marugan-Hernandez, V, Pegg, E, Tomley, F M   +6 more
core   +3 more sources

Future research to underpin successful peste des petits ruminants virus (PPRV) eradication [PDF]

, 2017
Peste des petits ruminants virus (PPRV) is a significant pathogen of small ruminants and is prevalent in much of Africa, the Near and Middle East and Asia.
Bouna Diop, Brian J. Willett, Dalan Bailey, Diallo, Diallo, Felix Njeumi, Michael D. Baron, Munir, Robinson, Roeder, Zahur   +10 more
core   +1 more source

Immunogenic potential of biogenic vs. synthetic selenium nanoparticles in vaccine candidate against methicillin-resistant Staphylococcus aureus

Vaccine: X
MRSA-related antimicrobial-resistant infections are a significant public health issue. Vaccination can prevent infection by inducing pathogen immunity. The surface-associated protein autolysin is a promising vaccination candidate. This study investigated
Alireza Ranjbariyan, Setareh Haghighat, Mohammad Hossein Yazdi, Sepideh Arbabi Bidgoli, Hedieh Moradi Tabriz, Mehdi Mahdavi   +5 more
doaj   +1 more source

Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice. [PDF]

, 2019
BackgroundAlzheimer disease (AD) is characterized by the accumulation of beta-amyloid (Aβ) plaques and neurofibrillary tangles composed of hyperphosphorylated tau, which together lead to neurodegeneration and cognitive decline.
Agadjanyan, Michael G, Antonyan, Tatevik, Blurton-Jones, Mathew, Chailyan, Gor, Coburn, Morgan A, Cribbs, David H, Danhash, Emma, Davtyan, Hayk, Ghochikyan, Anahit, Hovakimyan, Armine, Kiani Shabestari, Sepideh, Petrovsky, Nikolai, Petrushina, Irina, Svystun, Olga, Zagorski, Karen   +14 more
core  

A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]

, 2010
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe, Bernard, Julie, Bernex, Florence, Castagné, Nathalie, Deplanche, Martine, Deville, Sébastien, Dubosclard, Virginie, Dubuquoy, Catherine, Durand, Guillaume, Eléouët, Jean-François, Meyer, Gilles, Petit-Camurdan, Agnès, Riffault, Sabine, Schwartz-Cornil, Isabelle, Soulestin, Marion   +14 more
core   +2 more sources

Neutropenia as an adverse event following vaccination : results from randomized clinical trials in healthy adults and systematic review [PDF]

, 2016
Background : In the context of early vaccine trials aimed at evaluating the safety profile of novel vaccines, abnormal haematological values, such as neutropenia, are often reported.
Aerssens, Annelies, Anemona, Alessandra, Bodinham, Caroline L, Groth, Nicola, Launay, Odile, Leroux-Roels, Geert, Lewis, David, Loulergue, Pierre, Muturi-Kioi, Vincent, Podda, Audino, Saul, Allan   +10 more
core   +4 more sources

Use of recombinant proteins for the diagnosis and prevention of Mycoplasma bovis: a systematic review

Frontiers in Veterinary Science
IntroductionMycoplasma bovis is a highly contagious pathogen that causes various diseases in herd animals, negatively impacting reproduction, production, and milk yield. Effective diagnostic methods and vaccine development are critical for controlling M.
Camila Pachêco Gomes, Lucas Santana Coelho da Silva, Manoel Neres Santos Júnior, Maysa Santos Barbosa, Wanderson Souza Neves, Viviane Gomes Ribeiro, Bruno Lopes Bastos, Lucas Miranda Marques, Lucas Miranda Marques, Lucas Miranda Marques   +9 more
doaj   +1 more source

Recombinant vector vaccine evolution.

PLoS Computational Biology, 2019
Replicating recombinant vector vaccines consist of a fully competent viral vector backbone engineered to express an antigen from a foreign transgene.
James J Bull, Scott L Nuismer, Rustom Antia   +2 more
doaj   +1 more source