Results 111 to 120 of about 1,656,346 (308)

In vitro permissivity of bovine cells for wild-type and vaccinal myxoma virus strains [PDF]

, 2007
Myxoma virus (MYXV), a leporide-specific poxvirus, represents an attractive candidate for the generation of safe, non-replicative vaccine vector for non-host species.
Jean-Luc Duteyrat, Pignolet Béatrice, Stéphane Bertagnoli, Foucras Gilles, Béatrice Pignolet, Bertagnoli, Stéphane, Duteyrat, Jl, Aude Allemandou, Jacqueline Gelfi, Allemandou Aude, Bertagnoli Stéphane, Gelfi, Jacqueline, Foucras, Gilles, Duteyrat Jean-Luc, Gilles Foucras, Allemandou, Aude, Duteyrat, Jean-Luc, Pignolet, Béatrice, Gelfi Jacqueline   +18 more
core   +1 more source

Insights into the Pathogenesis and Development of Recombinant Japanese Encephalitis Virus Genotype 3 as a Vaccine

Vaccines
Japanese encephalitis virus (JEV), a flavivirus transmitted by mosquitoes, has caused epidemics and severe neurological diseases in Asian countries. In this study, we developed a cDNA infectious clone, pBAC JYJEV3, of the JEV genotype 3 strain (EF571853 ...
Jae-Yeon Park, Hye-Mi Lee, Sung-Hoon Jun, Wataru Kamitani, Onnuri Kim, Hyun-Jin Shin   +5 more
doaj   +1 more source

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

Advanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang, Wei Tong, Qiong Wu, Didi Wu, Yanrui Zhang, Qijuan Gao, Fangdong Li, Zhaoliang Zhang, Wenjie Wang, Chuankui Song, Enhua Xia   +10 more
wiley   +1 more source

Research note: Development of a recombinant duck enteritis virus vector expressing DHAV-3 VP1 and DTMUV prM/TE genes

Poultry Science
Duck enteritis virus ( DEV ) is a promising viral vector for vaccine development. In a previous study, an HDR-CRISPR/Cas9-based strategy was used to generate a recombinant virus, rDEV-DHAV-VP1, by inserting the VP1 gene of duck hepatitis A virus type 3 (
Wenfeng Jia, Zhi Wu, Aiqi Tan, Yuting Cheng, Qingkang Zhou, Shanyuan Zhu, Anping Wang   +6 more
doaj   +1 more source

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

The Hepatitis C virus : your part in its downfall : getting to know the virus and its host [PDF]

, 2005
The cloning of the genome of the Hepatitis C virus (HCV) in 1989 provided sensitive screening tools and specific diagnostic assays which helped health workers to limit viral spread and scientists to design effective anti-viral agents.
Pullicino, Edgar
core  

Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus. [PDF]

iScience, 2023
Chen DY, Turcinovic J, Feng S, Kenney DJ, Chin CV, Choudhary MC, Conway HL, Semaan M, Close BJ, Tavares AH, Seitz S, Khan N, Kapell S, Crossland NA, Li JZ, Douam F, Baker SC, Connor JH, Saeed M.   +18 more
europepmc   +1 more source

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

Advanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang, Guangbing Duan, Huihui Sun, Zhiyu Dong, Qiwei Wang, Xiaowei Li, Ying Chen, Shuchang Xu, Ying Huang   +8 more
wiley   +1 more source

Current status of recombinant duck enteritis virus vector vaccine research

Frontiers in Veterinary Science
Duck enteritis virus (DEV), the pathogen of duck viral enteritis, belongs to the α-herpesvirus subfamily. Like other herpesviruses, it has a large genome with multiple non-coding and non-essential regions for viral replication.
Wen-Feng Jia, An-Ping Wang, Zhi Wu, Xin-Nuo Lei, Yu-Ting Cheng, Shan-Yuan Zhu   +5 more
doaj   +1 more source

Recombinant Virus Quantification Using Single-Cell Droplet Digital PCR: A Method for Infectious Titer Quantification. [PDF]

Viruses, 2023
Korotkaja K, Zajakina A.
europepmc   +1 more source