Results 11 to 20 of about 548,158 (296)

Genetic variants in REC8, RNF212, and PRDM9 influence male recombination in cattle. [PDF]

open access: yesPLoS Genetics, 2012
We use >250,000 cross-over events identified in >10,000 bovine sperm cells to perform an extensive characterization of meiotic recombination in male cattle.
Cynthia Sandor   +5 more
doaj   +1 more source

The potential of shifting recombination hotspots to increase genetic gain in livestock breeding

open access: yesGenetics Selection Evolution, 2017
Background This study uses simulation to explore and quantify the potential effect of shifting recombination hotspots on genetic gain in livestock breeding programs.
Serap Gonen   +4 more
doaj   +1 more source

Recombination and Genetic Diversity

open access: yesTrends in Computational and Applied Mathematics, 2012
In this paper we present a spatial stochastic model for genetic recombination, that answers if diversity is preserved in an infinite population of recombinating individuals distributed spatially.
Thamara Carvalho Coutinho   +2 more
doaj   +1 more source

Genetic variation in recombination rate in the pig

open access: yesGenetics Selection Evolution, 2021
Background Meiotic recombination results in the exchange of genetic material between homologous chromosomes. Recombination rate varies between different parts of the genome, between individuals, and is influenced by genetics.
Martin Johnsson   +7 more
doaj   +1 more source

The extent of error-prone replication-restart by homologous recombination is controlled by Exo1 and checkpoint proteins [PDF]

open access: yes, 2014
Genetic instability, a hallmark of cancer, can occur when the replication machinery encounters a barrier. The intra-S phase checkpoint maintains stalled replication forks in a replication-competent configuration by phosphorylating replisome components ...
Ahn   +80 more
core   +2 more sources

SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination [PDF]

open access: yes, 2016
Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, but at the same time HR can lead to loss of heterozygosity and uncontrolled recombination can be genotoxic.
Lisby, Michael, Silva, Sonia
core   +1 more source

Mapping of meiotic recombination in human preimplantation blastocysts

open access: yesG3: Genes, Genomes, Genetics, 2023
Recombination is essential for physical attachments and genetic diversity. The Han Chinese population is the largest ethnic group worldwide, therefore, the construction of a genetic map regarding recombination for the population is essential.
Yuanlin Ma   +6 more
doaj   +1 more source

Multilocus sequence analysis of xanthomonads causing bacterial spot of tomato and pepper plants reveals strains generated by recombination among species and recent global spread of Xanthomonas gardneri [PDF]

open access: yes, 2015
Four Xanthomonas species are known to cause bacterial spot of tomato and pepper, but the global distribution and genetic diversity of these species are not well understood.
Bart, Rebecca   +12 more
core   +1 more source

Targeted recombination of homologous chromosomes using CRISPR‐Cas9

open access: yesFEBS Open Bio, 2023
CRISPR mutagenesis is an efficient way to disrupt specific target genes in many model organisms. We previously devised a targeted CRISPR recombination method to generate intragenic recombinants of alleles in Drosophila.
Wonseok Son, Ki Wha Chung
doaj   +1 more source

Allopolyploidization increases genetic recombination in the ancestral diploid D genome during wheat evolution

open access: yesCrop Journal, 2022
Genetic recombination produces new allelic combinations, thereby introducing variation for domestication. Allopolyploidization has increased the evolutionary potential of hexaploid common wheat by conferring the advantages of heterosis and gene ...
Hongshen Wan   +8 more
doaj   +1 more source

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