Results 21 to 30 of about 541,645 (230)
Targeted recombination of homologous chromosomes using CRISPR‐Cas9
CRISPR mutagenesis is an efficient way to disrupt specific target genes in many model organisms. We previously devised a targeted CRISPR recombination method to generate intragenic recombinants of alleles in Drosophila.
Wonseok Son, Ki Wha Chung
doaj +1 more source
Mapping of meiotic recombination in human preimplantation blastocysts
Recombination is essential for physical attachments and genetic diversity. The Han Chinese population is the largest ethnic group worldwide, therefore, the construction of a genetic map regarding recombination for the population is essential.
Yuanlin Ma +6 more
doaj +1 more source
Genetic recombination produces new allelic combinations, thereby introducing variation for domestication. Allopolyploidization has increased the evolutionary potential of hexaploid common wheat by conferring the advantages of heterosis and gene ...
Hongshen Wan +8 more
doaj +1 more source
The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]
Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X +6 more
core +2 more sources
Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum. [PDF]
In most organisms, the primary function of homologous recombination (HR) is to allow genome protection by the faithful repair of DNA double-strand breaks.
Buisson, Rémi +9 more
core +2 more sources
sequenceLDhot: Detecting Recombination Hotspots. [PDF]
Motivation: There is much local variation in recombination rates across the human genome—with the majority of recombination occuring in recombination hotspots—short regions of around ~2 kb in length that have much higher recombination rates than ...
Fearnhead, Paul
core +1 more source
Meiotic recombination generates genetic diversity but in most species the number of crossovers per meiosis is limited. Previous modeling studies showed that increasing recombination can enhance response to selection.
Elise Tourrette +3 more
doaj +1 more source
Recombination and Self-Adaptation in Multi-objective Genetic Algorithms [PDF]
This paper investigates the influence of recombination and self-adaptation in real-encoded Multi-Objective Genetic Algorithms (MOGAs). NSGA-II and SPEA2 are used as example to characterize the efficiency of MOGAs in relation to various recombination ...
Roboam, Xavier +2 more
core +2 more sources
Dynamics of male meiotic recombination frequency during plant development using Fluorescent Tagged Lines in Arabidopsis thaliana [PDF]
Meiotic homologous recombination plays a central role in creating genetic variability, making it an essential biological process relevant to evolution and crop breeding.
De Storme, Nico, Geelen, Danny, Li, Fan
core +1 more source
An Eco-Evolutionary approach of Adaptation and Recombination in a large population of varying size [PDF]
We identify the genetic signature of a selective sweep in a population described by a birth-and-death process with density dependent competition. We study the limit behaviour for large K, where K scales the population size.
Smadi, Charline
core +4 more sources

