ama1 genes of sympatric Plasmodium vivax and P. falciparum from Venezuela differ significantly in genetic diversity and recombination frequency. [PDF]
, 2008 BACKGROUND: We present the first population genetic analysis of homologous loci from two sympatric human malaria parasite populations sharing the same human hosts, using full-length sequences of ama1 genes from Plasmodium vivax and P.
Sutherland, Colin J +6 more
core +1 more source
PLoS ONE, 2020 Characterizing meiotic recombination rates across the genomes of nonhuman primates is important for understanding the genetics of primate populations, performing genetic analyses of phenotypic variation and reconstructing the evolution of human ...
Cheng Xue +7 more
doaj +1 more source
The coronavirus proofreading exoribonuclease mediates extensive viral recombination
bioRxiv, 2020 Coronaviruses (CoVs) emerge as zoonoses and cause severe disease in humans, demonstrated by the SARS-CoV-2 (COVID-19) pandemic. RNA recombination is required during normal CoV replication for subgenomic mRNA (sgmRNA) synthesis and generates defective ...
J. Gribble +8 more
semanticscholar +1 more source
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis
PLoS Genetics, 2015 Meiotic recombination is an essential biological process that generates genetic diversity and ensures proper segregation of chromosomes during meiosis. From a large USDA dairy cattle pedigree with over half a million genotyped animals, we extracted 186 ...
Li Ma +11 more
semanticscholar +1 more source
Sequence diversity and potential recombination events in the coat protein gene of Apple stem pitting virus. [PDF]
, 2011 The variability of the Apple stem pitting virus (ASPV) coat protein (CP) gene was investigated. The CP gene of ten virus isolates from apple and pear trees was sequenced.
Paweł Siedlecki +9 more
core +1 more source
Random-sequence genetic oligomer pools display an innate potential for ligation and recombination
eLife, 2018 Recombination, the exchange of information between different genetic polymer strands, is of fundamental importance in biology for genome maintenance and genetic diversification and is mediated by dedicated recombinase enzymes. Here, we describe an innate
Hannes Mutschler +7 more
doaj +1 more source
Recombination and Self-Adaptation in Multi-objective Genetic Algorithms [PDF]
, 2004 This paper investigates the influence of recombination and self-adaptation in real-encoded Multi-Objective Genetic Algorithms (MOGAs). NSGA-II and SPEA2 are used as example to characterize the efficiency of MOGAs in relation to various recombination ...
Régnier, Jérémi +5 more
core +1 more source
Identification and manipulation of the molecular determinants influencing poliovirus recombination.
PLoS Pathogens, 2013 The control and prevention of communicable disease is directly impacted by the genetic mutability of the underlying etiological agents. In the case of RNA viruses, genetic recombination may impact public health by facilitating the generation of new viral
Charles Runckel +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The effects of recombination rate on the distribution and abundance of transposable elements
, 2008 Transposable elements (TEs) often accumulate in regions of the genome with suppressed recombination. But it is unclear whether this pattern reflects a reduction in the efficacy of selection against deleterious insertions or a relaxation of ectopic ...
Charlesworth, Brian, Dolgin, Elie S.
core +1 more source