Results 101 to 110 of about 1,224,382 (402)

Meiotic Recombination: The Essence of Heredity.

open access: yesCold Spring Harbor Perspectives in Biology, 2015
The study of homologous recombination has its historical roots in meiosis. In this context, recombination occurs as a programmed event that culminates in the formation of crossovers, which are essential for accurate chromosome segregation and create new ...
N. Hunter
semanticscholar   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

A High-Resolution SNP Array-Based Linkage Map Anchors a New Domestic Cat Draft Genome Assembly and Provides Detailed Patterns of Recombination

open access: yesG3: Genes, Genomes, Genetics, 2016
High-resolution genetic and physical maps are invaluable tools for building accurate genome assemblies, and interpreting results of genome-wide association studies (GWAS).
Gang Li   +15 more
doaj   +1 more source

Scrambling eggs: Meiotic drive and the evolution of female recombination rates [PDF]

open access: yesarXiv, 2011
Theories to explain the prevalence of sex and recombination have long been a central theme of evolutionary biology. Yet despite decades of attention dedicated to the evolution of sex and recombination, the widespread pattern of sex-differences in the recombination rate is not well understood and has received relatively little theoretical attention ...
arxiv  

Spin dynamics and spin-dependent recombination of a polaron pair under a strong ac drive [PDF]

open access: yes, 2017
We study theoretically the recombination within a pair of two polarons in magnetic field subject to a strong linearly polarized ac drive. Strong drive implies that the Zeeman frequencies of the pair-partners are much smaller than the Rabi frequency, so that the rotating wave approximation does not apply. What makes the recombination dynamics nontrivial,
arxiv   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Electron-Ion Recombination Rate Coefficients and Photoionization Cross Sections for Astrophysically Abundant Elements. VII. Relativistic calculations for O VI and O VII for UV and X-ray modeling [PDF]

open access: yes, 2003
Aimed at ionization balance and spectral analysis of UV and X-ray sources, we present self-consistent sets of photoionization cross sections, recombination cross sections, and rate coefficients for Li-like O VI and He-like O VII.
Nahar, Sultana N., Pradhan, Anil K.
core   +2 more sources

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Extinction in genetic bit-string model with sexual recombination [PDF]

open access: yesarXiv, 2006
We have analyzed the relations between the mutational pressure, recombination and selection pressure in the bit-string model with sexual reproduction. For specific sets of these parameters we have found three phase transitions with one phase where populations can survive. In this phase, recombination enhances the survival probability.
arxiv  

Dimer-atom-atom recombination in the universal four-boson system

open access: yes, 2012
The dimer-atom-atom recombination process in the system of four identical bosons with resonant interactions is studied. The description uses the exact Alt, Grassberger and Sandhas equations for the four-particle transition operators that are solved in ...
A. Deltuva   +27 more
core   +1 more source

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