Results 111 to 120 of about 352,476 (324)
Recombination and peak jumping [PDF]
arXiv, 2014 We find an advantage of recombination for a category of complex fitness landscapes. Recent studies of empirical fitness landscapes reveal complex gene interactions and multiple peaks, and recombination can be a powerful mechanism for escaping suboptimal peaks.
arxiv
Variation in recombination frequency and distribution across eukaryotes: patterns and processes
Philosophical Transactions of the Royal Society B: Biological Sciences, 2017 Recombination, the exchange of DNA between maternal and paternal chromosomes during meiosis, is an essential feature of sexual reproduction in nearly all multicellular organisms.
J. Stapley +4 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren +8 more
wiley +1 more source
Recent advances on the non-coherent band surgery model for site-specific recombination [PDF]
arXiv, 2018 Site-specific recombination is an enzymatic process where two sites of precise sequence and orientation along a circle come together, are cleaved, and the ends are recombined. Site-specific recombination on a knotted substrate produces another knot or a two-component link depending on the relative orientation of the sites prior to recombination ...
arxiv
An efficient recombination system for chromosome engineering in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America, 2000 A recombination system has been developed for efficient chromosome engineering in Escherichia coli by using electroporated linear DNA. A defective lambda prophage supplies functions that protect and recombine an electroporated linear DNA substrate in the
Daiguan Yu +5 more
semanticscholar +1 more source
Machine stability and dosimetry for ultra‐high dose rate FLASH radiotherapy human clinical protocol
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Background The FLASH effect, induced by ultra‐high dose rate (UHDR) irradiations, offers the potential to spare normal tissue while effectively treating tumors. It is important to achieve precise and accurate dose delivery and to establish reliable detector systems, particularly for clinical trials needed to help the clinical transfer of FLASH‐
Patrik Gonçalves Jorge +9 more
wiley +1 more source
Photoionization and Recombination [PDF]
arXiv, 2000 Theoretically self-consistent calculations for photoionization and (e + ion) recombination are described. An identical eigenfunction expansion for the ion is employed in coupled channel calculations for both processes, thus ensuring consistently accurate cross sections and rates in an ab initio manner.
arxiv
Monte Carlo simulations of the inside-intron recombination [PDF]
, 2005 Biological genomes are divided into coding and non-coding regions. Introns are non-coding parts within genes, while the remaining non-coding parts are intergenic sequences. To study the evolutionary significance of recombination inside introns we have used two models based on the Monte Carlo method.
arxiv +1 more source
Evaluation of methods for detecting recombination from DNA sequences: Computer simulations
Proceedings of the National Academy of Sciences of the United States of America, 2001 Recombination is a key evolutionary process that shapes the architecture of genomes and the genetic structure of populations. Although many statistical methods are available for the detection of recombination from DNA sequences, their absolute and ...
D. Posada, K. Crandall
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Quantitative markers of cortical excitability may help identify responders to anti‐seizure medications (ASMs). We studied the relationship between ASM load and two electroencephalography (EEG) markers of cortical excitability in people with refractory epilepsy. Methods We included individuals with refractory focal epilepsy undergoing
Silvano R. Gefferie +7 more
wiley +1 more source