Results 51 to 60 of about 35,845 (227)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
A megbékélés és az emlékezés etikai kritériumai
Studia Universitatis Babeş-Bolyai. Theologia Reformata Transylvanica, 2020 Ethical Criteria of Reconciliation and Remembrance. Reconciliation is a fundamental concept of Christian theology, church practice and ecumenical social ethics. It is difficult to give a universally valid definition of reconciliation.
Sándor FAZAKAS
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Stylistyka, 2020 The aim of this article is to reflect on the multimodal constitution of German-French and Polish-German reconciliation in the context of linguistic research on collective memory.
Waldemar Czachur
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The German Occupier's Efforts to Germanize and Nazify Slovenian Youth in Gorenjska Through the School System [PDF]
Šolska KronikaIn the article, the author presents the efforts of the German authorities to Germanize Slovenian youth in Gorenjska through the German occupation school system during the German occupation from 1941 to 1945.
Damjan Hančič
doaj
Spiritual Leadership in the Upheaval of Settler Colonialism
ReligionsIn the current global landscape, characterized by religious fervour, social and political unrest, economic instability, and environmental challenges, spiritual leaders stand as pivotal agents of change. Their role is especially crucial in contexts marred
Salim J. Munayer
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source