Results 71 to 80 of about 100,543 (354)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The divine favour of the unworthy: When the fatherless son meets the Black Messiah
This article engages with Andries van Aarde’s 2001 work on the historical Jesus, Fatherless in Galilee: Jesus as Child of God. It poses the question whether Van Aarde succeeds in overcoming the shortcomings of Western, Euro-centric, male dominated ...
Allan A. Boesak
doaj +1 more source
2022 Swinburne Annual Reconciliation Lecture - Truth, Understanding and Transformation
Swinburne University of Technology and the National Centre for Reconciliation Practice is delighted to welcome Commissioner Sue-Anne Hunter, Deputy Chair Yoorrook Justice Commission, to deliver the 2022 Swinburne Annual Reconciliation Lecture on Thursday
Aunty Georgina Nicholson +3 more
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
»V imenu narodov Jugoslavije!« Procesi pred vojaškimi sodišči poleti 1945
In the aftermath of the Second World War, in May 1945, the first court-martial proceedings started in Slovenia; the convicted were mostly civilians, with very few military personnel among them.
Mateja Čoh Kladnik
doaj +1 more source
Student Leadership: Challenges and Possibilities
In my attempt to adhere to the request that I provide an interpretation of the theme for the session, ‘Critical Engagement, Innovation and Inclusivity’, and cognisant of the primary audience, I weave student leadership responsibilities, challenges and ...
Willy Nel
doaj +1 more source
Reconciliation in the Pauline Epistles. In my article, I deal with the concept of reconciliation in the Pauline Epistles. What does reconciliation mean?
Viktor KÓKAI-NAGY
doaj +1 more source
Medication reconciliation is recommended to be performed at every transition of medical care to prevent medication errors or adverse drug events. This study investigated the impact of pharmacy‐led medication reconciliation on medication discrepancies and
Y. Choi, Hyunah Kim
semanticscholar +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source

