Results 71 to 80 of about 510,767 (334)

Unifying Parsimonious Tree Reconciliation

open access: yes, 2013
Evolution is a process that is influenced by various environmental factors, e.g. the interactions between different species, genes, and biogeographical properties.
A.C. Berglund-Sonnhammer   +28 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A megbékélés és az emlékezés etikai kritériumai

open access: yesStudia Universitatis Babeş-Bolyai. Theologia Reformata Transylvanica, 2020
Ethical Criteria of Reconciliation and Remembrance. Reconciliation is a fundamental concept of Christian theology, church practice and ecumenical social ethics. It is difficult to give a universally valid definition of reconciliation.
Sándor FAZAKAS
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multimodalne profilowanie pojednania w dyskursach pamięci. Analiza na przykładzie internetowych zapowiedzi obchodów 50. rocznicy niemiecko-francuskiej Mszy Pojednania w Reims i 25. rocznicy polsko-niemieckiej Mszy Pojednania w Krzyżowej

open access: yesStylistyka, 2020
The aim of this article is to reflect on the multimodal constitution of German-French and Polish-German reconciliation in the context of linguistic research on collective memory.
Waldemar Czachur
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The German Occupier's Efforts to Germanize and Nazify Slovenian Youth in Gorenjska Through the School System [PDF]

open access: yesŠolska Kronika
In the article, the author presents the efforts of the German authorities to Germanize Slovenian youth in Gorenjska through the German occupation school system during the German occupation from 1941 to 1945.
Damjan Hančič
doaj  

Spiritual Leadership in the Upheaval of Settler Colonialism

open access: yesReligions
In the current global landscape, characterized by religious fervour, social and political unrest, economic instability, and environmental challenges, spiritual leaders stand as pivotal agents of change. Their role is especially crucial in contexts marred
Salim J. Munayer
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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