Results 71 to 80 of about 1,605,665 (319)

Facilitating Development Research: Suggestions for Recruiting and Re-Recruiting Children and Families

Frontiers in Psychology, 2017
Recruiting children and families for research studies can be challenging, and re-recruiting former participants for longitudinal research can be even more difficult, especially when a study was not prospectively designed to encompass continuous data ...
Lisa B. Hurwitz, Kelly L. Schmitt, Kelly L. Schmitt, Megan K. Olsen   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Participant recruitment to FiCTION, a primary dental care trial – survey of facilitators and barriers [PDF]

, 2014
Objective: To identify reasons behind a lower than expected participant recruitment rate within the FiCTION trial, a multi-centre paediatric primary dental care randomised controlled trial (RCT).Subjects (materials) and methods: An online survey, based ...
Clarkson, J, Clarkson, J., Maguire, A, Innes, N.; id_orcid, A. Keightley, Maguire, A., J. Clarkson, Clarkson, J.; id_orcid, A. Maguire, Speed, C, N. Innes, Keightley, A, C. Speed, Keightley, A., Speed, C., Innes, N, Innes, N.   +16 more
core   +1 more source

Components of population growth for Arctic foxes at a large Arctic goose colony: the relative contributions of adult survival and recruitment

Polar Research, 2017
The abundance and distribution of animals often vary dramatically among years in Arctic environments. Such variation, in turn, is closely related to changes in food abundance and its effect on vital rates such as survival and recruitment.
Gustaf Samelius, Ray T. Alisauskas
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Three controlled trials of interventions to increase recruitment to a randomized controlled trial of mobile phone based smoking cessation support. [PDF]

, 2010
BACKGROUND: Recruitment is a major challenge for trials but there is little evidence regarding interventions to increase trial recruitment. We report three controlled trials of interventions to increase recruitment to the Txt2stop trial.
Free, Caroline, Robertson, Steven, Knight, Rosemary, Hoile, Elizabeth   +3 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The National Children’s Study: Recruitment Outcomes Using the Provider-Based Recruitment Approach

, 2016
Objective: In 2009, the National Children's Study (NCS) Vanguard Study tested the feasibility of household-based recruitment and participant enrollment using a birth-rate probability sample.
Robbins, James M., Cislo, Kendall K., Cherry, Debra, Reynolds, Simone A., Siega-Riz, Anna Maria, Buka, Stephen, Norman, Gwendolyn S., Wadlinger, Sandra, Dudley, Donald J., Hale, Daniel E., Wyatt, Sharon B., Walker, Cheryl K., McElfish, Pearl Anna   +12 more
core   +1 more source

Evaluation of different recruitment and randomisation methods in a trial of general practitioner-led interventions to increase physical activity : a randomised controlled feasibility study with factorial design [PDF]

, 2014
Background: Interventions promoting physical activity by General Practitioners (GPs) lack a strong evidence base. Recruiting participants to trials in primary care is challenging.
Murphy, Marie, Thorogood, Margaret, Warren, Fiona C., Taylor, Rod (Rod S.), John L Campbell, Sharp, Debbie J, Marie Murphy, Campbell, John L, Bryant, Susan, Caroline Huxley, Searle, A, Taylor, RS, Turner, KM, Turner, Katrina M., Warren, Fiona C, Warren, FC, Susan Bryant, Sharp, Deborah J., Tim A Holt, Murphy, MH, Sharp, D. J. (Deborah Jane Lister), Kate Stych, Huxley, Caroline J., Holt, TA, Taylor, Rod S, Turner, Katrina M, Stych, Kate, Hillsdon, M, Stych, K, Katrina M Turner, Huxley, Caroline, Holt, KA, Thorogood, M, Holt, Tim A, Bryant, S, Margaret Thorogood, Sharp, DJ, Melvyn Hillsdon, Taylor, Rod S., Searle, Aidan, Campbell, JL, Campbell, John L., Holt, Tim A., Murphy, M, Rod S Taylor, Fiona C Warren, Huxley, C, Aidan Searle, Hillsdon, Melvyn, Deborah J Sharp   +49 more
core   +1 more source

Tunneling nanotube-mediated stem cell immunomodulation dysfunction promotes adipose inflammation and insulin resistance in GDM

Cell Reports
Summary: Adipose-derived stem cells (ADSCs) represent a promising therapeutic resource, yet their immunometabolic regulation remains poorly defined. Here, we reveal a tunneling nanotube (TNT)-mediated communication mechanism between ADSCs and adipose ...
Bingnan Chen, Xuyang Chen, Jianxin Li, Ruohan Hu, Lijun Yang, Hongli Li, Xinmi Liu, Richard D. Cannon, Richard Saffery, Boris Novakovic, Hongbo Qi, Hua Zhang, Xiaobo Zhou   +12 more
doaj   +1 more source