Results 91 to 100 of about 2,923,121 (309)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

A List of Best Practices That May Improve the Use of Telephone Interviews During the Recruitment Process

open access: yesEvidence Based Library and Information Practice, 2009
A Review of: Engel, Debra, and Sarah Robbins. "Telephone Interviewing Practices within Academic Libraries." Journal of Academic Librarianship 35.2 (2009): 143-51. Objective – To investigate the use of telephone interviews in academic libraries and
David Herron, Lotta Haglund
doaj   +1 more source

Determinants Of Jobs Seekers’ Intention In Using E-Recruitments: Insight From Indonesia [PDF]

open access: yes, 2012
In a digital world, job seekers prefer to use e-recruitment in looking for a vacancy. Thus, the explanation of the determinants of their attitude in using this technology is left unobserved.
Rayenda , Brahmana   +1 more
core  

Porites superfusa mortality and recovery from a bleaching event at Palmyra Atoll, USA. [PDF]

open access: yes, 2017
BackgroundThe demography of a coral colony is not a binary trajectory of life and death. Based on the flexibility afforded by colonial organization, most reef-building corals employ a variety of dynamic survival strategies, including growth and shrinkage.
Furby, Kathryn Anne   +2 more
core   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Decentralized nursing education in Northern Norway: towards a sustainable recruitment and retention model in rural Arctic healthcare services

open access: yesInternational Journal of Circumpolar Health, 2013
Introduction. Decentralized nursing education (DNE) was established at Tromsø University College in 1990 and has since become a part of the bachelor programme in nursing at UiT The Arctic University of Norway.
Bente Norbye, Mari Wolff Skaalvik
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The relationship between smolt and postsmolt growth for Atlantic salmon (Salmo salar) in the Gulf of St. Lawrence [PDF]

open access: yes, 2006
The interaction of ocean climate and growth conditions during the postsmolt phase is emerging as the primary hypothesis to explain patterns of adult recruitment for individual stocks and stock complexes of Atlantic salmon (Salmo salar). Friedland et al. (
Clarke, Lora M.   +3 more
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Comparing survey and assessment data: Consequences for stock evaluation of Northeast Arctic Greenland halibut

open access: yesScientia Marina, 2003
Based on VPA-estimates of abundance, survey data and commercial catch statistics of Northeast Arctic Greenland halibut (Reinhardtius hippoglossoides Walbaum), the paper describes trends by year-class and age in the distribution of Greenland halibut ...
Ole Thomas Albert, Åge S. Høines
doaj   +1 more source

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