Results 71 to 80 of about 449,476 (220)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effects of lung recruitment maneuvers on splanchnic organ perfusion during endotoxin-induced pulmonary arterial hypertension

, 2010
Lung recruitment maneuvers (RMs), used to reopen atelectatic lung units and to improve oxygenation during mechanical ventilation, may result in hemodynamic impairment. We hypothesize that pulmonary arterial hypertension aggravates the consequences of RMs
Rothen, Hans Ulrich, Bracht, Hendrik, Krejci, Vladimir, Daudel, Fritz, Gorrasi, José, Brandt, Sebastian, Jakob, Stephan M, Takala, Jukka   +7 more
core   +1 more source

Improved oxygenation and lung compliance with recruitment maneuvers in robotic prostate surgery: A randomized trial [PDF]

Journal of Biomedical & Clinical Research
Background: This randomized controlled trial investigated the effects of recruitment maneuvers on arterial oxygenation and lung compliance in patients undergoing robotic-assisted prostatectomy in the steep Trendelenburg position.
Halil Islamoglu, Bilge Aslan, Ayça Dumanlı Özcan, Abdülkadir But   +3 more
doaj   +3 more sources

The Contribution of Surface Tension-Dependent Alveolar Septal Stress Concentrations to Ventilation-Induced Lung Injury in the Acute Respiratory Distress Syndrome

Frontiers in Physiology, 2020
In the acute respiratory distress syndrome (ARDS), surface tension, T, is likely elevated. And mechanical ventilation of ARDS patients causes ventilation-induced lung injury (VILI), which is believed to be proportional to T.
Carrie E. Perlman
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Utility of bedside lung ultrasound for assessment of lung recruitment in a case of acute respiratory distress syndrome

Lung India, 2019
Lung recruitment maneuvers are rescue measures commonly used to improve oxygenation in severely hypoxemic patients with acute respiratory distress syndrome (ARDS), who fail to improve on standard treatment.
Abhijeet Singh, Ayush Gupta, Manas Kamal Sen, Jagdish Chander Suri, Shibdas Chakrabarti, Dipak Bhattacharya   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

State of Ohio ... the employer of choice

, 2004
[Rev.].; Title from PDF cover (viewed Jan. 14, 2004).; "Hrd/rev8.30.04"--P. [4] of cover.; Harvested from the web on 1/14/05[Rev.]
Ohio. Centralized Recruitment Office
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Doppler images of intra-pulmonary shunt within atelectasis in anesthetized children

Critical Ultrasound Journal, 2016
Background Doppler images of pulmonary vessels in pulmonary diseases associated with subpleural consolidations have been described. Color Doppler easily identifies such vessels within consolidations while spectral Doppler analysis allows the ...
Cecilia M. Acosta, Gerardo Tusman, Mauro Costantini, Camila Echevarría, Sergio Pollioto, Diego Abrego, Fernando Suarez-Sipmann, Stephan H. Böhm   +7 more
doaj   +1 more source