Results 61 to 70 of about 449,476 (220)

Ultrasonographic Evaluation of the Impact of Positive End-Expiratory Pressure and Pulmonary Recruitment on Diaphragmatic Function in Laparoscopic Surgery Patients

RGUHS Journal of Medical Sciences
Background Evidence suggests that gas insufflation during laparoscopic surgery may compromise diaphragmatic function potentially leading to postoperative respiratory challenges.
Namratha Chandra, Saraswathi Nagappa, Sumaiya Sabreen, Mohsina Yasmeen   +3 more
doaj   +1 more source

Alveolar recruitment maneuver in refractory hypoxemia and lobar atelectasis after cardiac surgery: A case report

Journal of Cardiothoracic Surgery, 2012
Objective This case report describes an unusual presentation of right upper lobe atelectasis associated with refractory hypoxemia to conventional alveolar recruitment maneuvers in a patient soon after coronary artery bypass grafting surgery.
Herbst-Rodrigues Marcus, Carvalho Vitor, Abrahao Ludhmila, Nozawa Emilia, Feltrim Maria Ignez, Gomes-Galas Filomena Regina   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Expert opinion document: “Electrical impedance tomography: applications from the intensive care unit and beyond”

Journal of Anesthesia, Analgesia and Critical Care, 2022
Mechanical ventilation is a life-saving technology, but it can also inadvertently induce lung injury and increase morbidity and mortality. Currently, there is no easy method of assessing the impact that ventilator settings have on the degree of lung ...
Michela Rauseo, Elena Spinelli, Nicolò Sella, Douglas Slobod, Savino Spadaro, Federico Longhini, Antonino Giarratano, Cinnella Gilda, Tommaso Mauri, Paolo Navalesi, SIAARTI Study Group   +10 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Lung recruitment mechanics: coalescing tissue strains with organ expansion

Respiratory Research
Background Recruitment maneuvers are used to prevent atelectasis, or partial lung collapse, and to help prevent ventilator induced lung injury. Recruitment techniques remain a topic of debate due to the possibility for damage as they necessitate higher ...
M. Shankel, T. M. Nelson, K. A. M. Quiros, J. Bebawy, C. A. Mariano, T. Biddle, D. D. Lo, M. Eskandari   +7 more
doaj   +1 more source

Postural lung recruitment assessed by lung ultrasound in mechanically ventilated children

Critical Ultrasound Journal, 2017
Background Atelectasis is a common finding in mechanically ventilated children with healthy lungs. This lung collapse cannot be overcome using standard levels of positive end-expiratory pressure (PEEP) and thus for only individualized lung recruitment ...
Gerardo Tusman, Cecilia M. Acosta, Stephan H. Böhm, Andreas D. Waldmann, Carlos Ferrando, Manuel Perez Marquez, Fernando Suarez Sipmann   +6 more
doaj   +1 more source

Airway pressure release ventilation benefits in a patient with chronic lymphocytic leukemia

Indian Journal of Respiratory Care, 2020
Background: Airway pressure release ventilation (APRV) is a novel mode of mechanical ventilation (MV) used in the treatment of acute respiratory distress syndrome (ARDS) for patients with severe hypoxemia with a strategy to prevent ventilator-induced ...
Oluwasegun Albert, Abdulraheem Alzahrani, Abdullah Almutairi   +2 more
doaj   +1 more source