Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Assessment of recent eastern oyster (Crassostrea virginica) reef restoration projects in the Great Bay Estuary, New Hampshire: Planning for the future [PDF]
, 2016 Current oyster populations in New Hampshire total less than 10% of what they were in the 1980s, and the causal factors for the declines include disease, sedimentation, and human harvest.
Grizzle, Raymond E., Ward, Krystin M.
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Recruiting Participants in Vulnerable Situations: A Qualitative Evaluation of the Recruitment Process in the EFFICHRONIC Study. [PDF]
Int J Environ Res Public Health, 2022 Serrano-Gallardo P +3 more
europepmc +1 more source
IMPROVEMENT MANAGEMENT OF TEACHER RESOURCE AMONG VOCATIONAL HIGH SCHOOL BASED ON INTERNATIONAL STANDARD SCHOOL INVEST (INDONESIA VOCATIONAL EDUCATION STRENGTHENING) IN YOGYAKARTA [PDF]
, 2012 This education research aimed to: (1) find an overview of resource about teacher’s resource improvement management in vocational high school based on international INVEST in Yogyakarta, (2) find the effectiveness for the implementation of quality ...
Dian Rustamana Indra Putra, Dian Rustamana Indra Putra
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Review of the recruitment process for a large investigator-initiated trial in early Parkinson's disease. [PDF]
Trials, 2022 Verschuur CVM, Donovan JL, de Bie RMA.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Are adolescents and young adults in substance use disorder treatment as engaged in the research recruitment process as those in general behavioral health treatment? [PDF]
Contemp Clin Trials, 2022 Taubin D +5 more
europepmc +1 more source
Name Discrimination in the Recruitment Process by Recruiters
International Journal of Social Science Studies, 2015 Literature reviews have brought attention to the discrimination towards names in the recruitment process by recruiters where these individuals are not considered for employment. In order to examine this phenomenon from the literature, an ethnographic study was conducted of the perceptions of recruiters through participant observation and a semi ...
openaire +2 more sources