Results 61 to 70 of about 113,224 (248)

Nanotransfersomes-loaded thermosensitive in situ gel as a rectal delivery system of tizanidine HCl: preparation, in vitro and in vivo performance

open access: yesDrug Delivery, 2017
The purpose of the current study was to develop tizanidine HCl (TIZ; a myotonolytic agent used for treatment of spasticity) loaded nanotransfersomes intended for rectal administration, aiming to bypass the hepatic first-pass metabolism.
Fatma A. Moawad   +2 more
doaj   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki   +6 more
wiley   +1 more source

A conservative approach in a child with haematuria after accidental rectal impalement trauma

open access: yesAfrican Journal of Paediatric Surgery, 2015
We present a case of an 11-year-old boy with haematuria after traumatic rectal insertion of a sharp metal stick. It demonstrates that an expectative management with close observation can be considered in patients with rectal impalement trauma presenting ...
Josephine Schijns, Frans Berend Plötz
doaj   +1 more source

Impact of D3 lymph node dissection on upstaging and short-term survival in clinical stage I right-sided colon cancer

open access: yesAsian Journal of Surgery, 2021
Summary: Background: D3 lymph node dissection is becoming the standard procedure for the treatment of advanced right colon cancer and has shown increasing evidence of its oncologic benefit.
Ji-Seon Kim   +11 more
doaj   +1 more source

Rheumatoid arthritis, frailty, and outcomes of surgical hospitalizations: A national population‐based analysis

open access: yesArthritis Care &Research, Accepted Article.
OBJECTIVE Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective non‐cardiac surgery. METHODS We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including ...
Ali Yazdanyar   +5 more
wiley   +1 more source

Less Silence, More Science: Advocacy to Make Rectal Microbicides a Reality [PDF]

open access: yes, 2008
Since its creation in 2005, International Rectal Microbicide Advocates (IRMA) has seen significant growth and success. From a handful of advocates, IRMA has built a network of well over 500 advocates, researchers, and policy makers from 40 countries on ...
Marc-Andre LeBlanc
core   +2 more sources

Isolation of Serpulina pilosicoli from rectal biopsy specimens showing evidence of intestinal spirochetosis [PDF]

open access: yes, 1998
Histologic evidence of intestinal spirochetosis (IS) was found in 22 of 41 (53.7%) rectal biopsy specimens from homosexual men attending a sexually transmitted diseases clinic. Serpulina pilosicoli was cultured from 11 of the IS-positive biopsy specimens
Gilbert, G.L.   +4 more
core  

Electrochemical Pathways for Nitrate Conversion to Ammonia: From Environmental Challenges to Ammonia Economy

open access: yesAdvanced Functional Materials, EarlyView.
This perspective presents recent advances in electrocatalytic nitrate reduction, focusing on reaction mechanisms, catalyst design, and electrolyzer configurations. Key challenges in selectivity, stability, and practical wastewater treatment are highlighted, while future directions for advancing sustainable ammonia synthesis and nitrate remediation are ...
Xintong Li   +9 more
wiley   +1 more source

An evaluation of 3D modelling in patients with locally advanced pelvic malignancy undergoing surgical resection

open access: yesFrontiers in Oncology
BackgroundSurgery for locally advanced pelvic malignancy is complex, requiring careful operative planning and effective patient consent. Traditional two-dimensional (2D) imaging can limit understanding of tumour-organ relationships for both clinicians ...
Rachael Elizabeth Clifford   +7 more
doaj   +1 more source

Gene and microRNA expression predictive of tumour response in patients treated with preoperative chemoradiotherapy for rectal cancer [PDF]

open access: yes, 2013
Background Preoperative chemoradiotherapy (pCRT) followed by surgery is the standard treatment for locally advanced rectal cancer (LARC). However, the response to pCRT is not uniform, and there is no effective method to predict tumour response to pCRT ...
Maretto, I
core  

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