Results 161 to 170 of about 153,838 (196)
Precision Radiation Oncology, EarlyView.Ultra‐hypofractionated three‐dose‐level radiotherapy allows safe dose escalation to dominant intraprostatic lesions near the urethra while maintaining full coverage of pelvis and prostate and respecting urethral and organ‐at‐risk constraints. Abstract This planning study evaluated ultra‐hypofractionated three‐dose‐level radiotherapy for prostate cancer
Annalisa Muscato +4 more
wiley +1 more source
Precision Radiation Oncology, EarlyView.Magnetic resonance (MR)‐guided online adaptive radiotherapy requires skill in online adaptive treatment planning. This study demonstrated that radiation therapists, with appropriate training, can consistently produce high‐quality adaptive plans concordant with those created by medical physicists for treatment on a 1.5 Tesla MR‐Linac.
Eva Birring +10 more
wiley +1 more source
The Prostate, EarlyView.ABSTRACT Introduction This paper reports the development and application of an artificial intelligence (AI)–led approach to large volume MRI data curation and image segmentation of periprostatic adipose tissue (PPAT) in prostate cancer (PCa)–free men from the UK Biobank. We report how PPAT was defined, radiomics features of PPAT extracted, and explored
Angela O'Neill +9 more
wiley +1 more source
The Prostate, EarlyView.ABSTRACT Background For prostate cancer (PCa), early diagnosis and biomarker‐based patient stratification can improve clinical decision‐making and post‐treatment prognosis. PCa biomarkers are best validated in tissue following comprehensive histopathologic review; however, urinary biomarkers can be obtained non‐invasively and are therefore safer and ...
Yuandong Xing +11 more
wiley +1 more source
Urinary Soluble Collagen Levels Are Associated With Moderate/Severe LUTS
The Prostate, EarlyView.ABSTRACT Background Expansion of the stromal compartment of the prostate concurrent with fibroblast activation and increased collagenization is now recognized as a pathobiology likely contributing to Lower Urinary Tract Symptoms (LUTS). However, approaches to quantitatively and, ideally, non‐invasively, assess prostatic collagenization in vivo are not ...
Marissa Sarna‐McCarthy +5 more
wiley +1 more source
The Prostate, EarlyView.ABSTRACT Background Chronic exposure to androgen receptor (AR)‐targeted therapies can drive lineage plasticity, leading to treatment resistance and neuroendocrine prostate cancer (NEPC), characterized by loss of AR expression and acquisition of neuroendocrine (NE) markers including synaptophysin (SYP). We evaluated concordance between circulating tumor
Ethan Lo +16 more
wiley +1 more source
Phytotherapy Research, EarlyView.Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei +4 more
wiley +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Green tea catechins have chemopreventive potential; however, the clinical evidence remains inconsistent. This review evaluated the effects of supplementation with green tea derivatives on chemoprevention at different stages of carcinogenesis. PubMed, Embase, Web of Science, Scopus, the Cochrane Library, CINAHL, and Google Scholar were searched
Thaís Moreira Machado +6 more
wiley +1 more source
Phytotherapy Research, EarlyView.Overview of systematic reviews evaluating the benefits and harms of herbal medicines for management of ARIs. ABSTRACT Hundreds of herbal medicines are currently marketed for the management of acute respiratory infections (ARIs). However, there is uncertainty about their benefits and harms, and clinical guidance remains unclear.
Fariba Aghajafari +11 more
wiley +1 more source