Results 31 to 40 of about 153,838 (196)

Laparoscopic total pelvic exenteration and perineal amputation with wet colostomy. A case report

open access: yesJournal of Coloproctology, 2012
Advanced rectal tumors can be treated with curative intent by surgical resection of the rectum including other pelvic organs. The reconstruction of the urinary and gastrointestinal tracts depends on the distance between the tumor and the anus, the ...
Juliano Alves Figueiredo   +5 more
doaj   +1 more source

Rectal Microbicides 101 [PDF]

open access: yes, 2010
A fact sheet describing what rectal microbicides are, why they are needed, and the status of research and ...

core   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Endoscopic resection of rectal granular-cell tumor using elastic band ligation [PDF]

open access: yes, 2016
Granular cell tumor (GCT) is a rare neoplasm that develops in the gut's submucosal layer. We report the case of a male with a history of surgically excised colon neoplasm where a rectal polyp was identified during a follow-up endoscopy.
Domínguez-Cañete,Juan José   +4 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Early outcomes of 100 patients with laparoscopic resection for rectal neoplasm

open access: yes, 2004
Background: Laparoscopic resection has been shown to be a feasible option in patients with colorectal diseases. However, there have been only a few studies on laparoscopic resection for rectal neoplasm. This report aimed to evaluate the early outcomes of
Tung, HM   +5 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Leiomyosarcoma of the rectosigmoid junction, a case report

open access: yesRadiology Case Reports, 2020
Leiomyosarcomas are a rare type of neoplasm of the digestive tract with an estimated presentation of 0.1% predominantly between the fifth and sixth decade of life [1]. We report the case of a 61 years old male patient without previous medical conditions,
Tania Lisseth Mercado Avendano, MD   +1 more
doaj   +1 more source

Chemical Shift-Encoded Sequence (IDEAL-IQ) and Amide Proton Transfer (APT) MRI for Prediction of Histopathological Factors of Rectal Cancer

open access: yesBioengineering, 2023
To investigate whether parameters from IDEAL-IQ/amide proton transfer MRI (APTWI) could help predict histopathological factors of rectal cancer. Preoperative IDEAL-IQ and APTWI sequences of 67 patients with rectal cancer were retrospectively analyzed ...
Yang Peng   +6 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

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