Approach of Colorectal Surgeons to Lower Rectal Adenocarcinomas: Results from the Turkish Society of Colon and Rectal Surgery Database [PDF]
Aim: This study aimed to analyze surgical preferences and outcomes among patients with lower rectal tumors in Türkiye using data from the national Colorectal Cancer Database of the Turkish Society of Colon and Rectal Surgery (TSCRS).
Mehmet Ali Koç +14 more
core +1 more source
Feasibility and morbidity of combined hyperthermia and radiochemotherapy in recurrent rectal cancer - Preliminary results [PDF]
Background: The local recurrence rate of colorectal cancer has been significantly reduced due to the use of combined radiochemotherapy. Despite this improvement regarding locally advanced tumour recurrences, the treatment strategy for pre-treated ...
Schaffer, P.M. +21 more
core +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
The value of colonoscopy to assess rectal bleeding in patients referred from Primary Care Units [PDF]
Objectives: rectal bleeding is very common in the general population. It is produced mainly because of benign disease originating in the anus and the rectum.
Gil-Molet,A. +7 more
core +1 more source
AimTo determine whether adding consolidation capecitabine chemotherapy without lengthening the waiting period influences pathological complete response (pCR) and short-term outcome of locally advanced rectal cancer (LARC) receiving neoadjuvant ...
Yifang Fang +5 more
doaj +1 more source
Radio-chemotherapy as a preoperative treatment for advanced rectal cancer. Evaluation of down-staging and morbidity [PDF]
Background: The standard therapy for patients with clinically resectable rectal cancer is generally considered to be surgery, If the patient is diagnosed with advanced disease, postoperative radiochemotherapy (RCT) is usually recommended. In our study we
Wilkowski, R. +4 more
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Lymph node micrometastasis in stage I and II rectal cancer [PDF]
Purpose The aim of this study was to determine the rate of lymph node (LN) micrometastasis in patients with stage I and II rectal cancer. Methods One hundred eighty patients with either stage I or II rectal carcinoma who underwent curative resection ...
Hye-Yoon Choi +3 more
doaj +1 more source
Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer
Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman +7 more
wiley +1 more source
Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis +7 more
wiley +1 more source

