Results 191 to 200 of about 549,282 (362)

Dietary Riboflavin Supplementation Suppresses Colorectal Cancer Progression by Restoring the Function Effector of CD8+ T Cells

Food Frontiers, EarlyView.
Intestinal tumor cells impair CD8+T cell cytotoxicity by upregulating riboflavin uptake, a process reversible with riboflavin supplementation ABSTRACT Tumor cells have a competitive edge in nutrient uptake, leading to immune cell nutrient deprivation within the tumor microenvironment (TME) and suppressing anti‐tumor immunity.
Lining Chen, Yao Lu, Peng Xue, Yingying Lin, Zhen Zhang, Yuqi Wang, Yuning Zhang, Heng Quan, Yiran Wang, Huiyuan Guo   +9 more
wiley   +1 more source

Global Burden of Disease Due to High Body Mass Index and Projections to 2040: A Study Based on the Global Burden of Disease Study 2019

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Background The prevalence of high body mass index (BMI) contributes to an increased risk of various diseases. This study aimed to identify global disease burden trends associated with high BMI from 1990 to 2019 and forecasts up to 2040. Methods Using data from the global burden of disease (GBD) 2019 study, we analysed the number and ratio of ...
Eun‐Ji Kim, Yoonseo Park, Sewon Park, Mihajlo Jakovljevic, Munjae Lee   +4 more
wiley   +1 more source

Cost effectiveness analysis of prostate cancer screening strategies in Germany: A microsimulation study

International Journal of Cancer, EarlyView.
What's New? Prostate cancer is a significant health and economic concern in Germany. In particular, screening methods require greater optimisation to prevent overdiagnosis and unnecessary procedures and to ensure clinical benefit. Here, prostate cancer screening strategies were evaluated to determine which are most effective in terms of cost and health
Muchandifunga Trust Muchadeyi, Shuang Hao, Karla Hernandez‐Villafuerte, Shah Alam Khan, Nikolaus Becker, Agne Krilaviciute, Petra Seibold, Roman Gulati, Peter Albers, Michael Schlander, Mark Clements   +10 more
wiley   +1 more source

Surgical outcomes of robotic transanal minimally invasive surgery for selected rectal neoplasms: A single-hospital experience.

Asian Journal of Surgery, 2019
Yan-Jiun Huang, Yu-Min Huang, Wei-Lin Wang, Yiu-Shun Tong, Wayne Hsu, P. Wei   +5 more
semanticscholar   +1 more source

Fragility Index analysis for robustness of evidence in Randomized Controlled Trials in National Comprehensive Cancer Network (NCCN) guidelines for rectal cancer

International Journal of Cancer, EarlyView.
What's New? Data from randomized controlled trials (RCTs) forms a foundation for rectal cancer treatment guidelines. The reliability of such data is therefore essential for evidence‐based clinical decision‐making. This study assessed the robustness of RCTs cited in the latest National Comprehensive Cancer Network (NCCN) guidelines for rectal cancer ...
Nir Horesh, Justin Dourado, Peter Rogers, Pauline Aeschbacher, Zoe Garoufalia, Rachel Gefen, Ebram Salama, Sameh Hany Emile, Steven D. Wexner   +8 more
wiley   +1 more source

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

International Journal of Cancer, EarlyView.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li, Yijin Yu, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao   +7 more
wiley   +1 more source

Claudin expression in rectal well-differentiated endocrine neoplasms (carcinoid tumors)

, 1994
Okabe
openalex   +2 more sources

Genetic variants linked to type 2 diabetes in CDKN1B and TCF7L2 influence survival outcomes in metastatic colorectal cancer

International Journal of Cancer, EarlyView.
What's New? Multiple genetic polymorphisms characteristic of type 2 diabetes (T2D) have been associated with unfavorable prognostic outcomes in individuals with both T2D and metastatic colorectal cancer. This study evaluated the impact of T2D genetic polymorphisms on metastatic colon cancer prognosis in a cohort of non‐diabetic patients.
Raffaella Ruggiero, Alessandro Ottaiano, Madhura Tathode, Roberto Sirica, Annabella Di Mauro, Monica Ianniello, Nadia Petrillo, Massimiliano Berretta, Silvia Zappavigna, Amalia Luce, Michele Caraglia, Giovanni Savarese   +11 more
wiley   +1 more source

Immunohistochemical demonstration of the type III intermediate filament peripherin in human rectal mucosae and well-differentiated endocrine neoplasms

, 2007
Mitsuaki Ishida, Ryoji Kushima, Tokuhiro Chano, Hidetoshi Okabe   +3 more
openalex   +2 more sources

Ramucirumab‐containing chemotherapy for patients with gastrointestinal neuroendocrine carcinoma refractory/intolerant to platinum‐based chemotherapy: A multicenter observational retrospective study (WJOG13420G)

International Journal of Cancer, EarlyView.
What's New? Platinum‐based chemotherapy is the first‐line treatment for unresectable gastrointestinal neuroendocrine carcinoma (NEC). Which treatments are most effective following platinum‐based regimens remains unclear. In this study, the authors compared clinical outcomes between NEC patients who received second‐ or later‐line treatments either with ...
Yuki Matsubara, Toshiki Masuishi, Waki Hosoda, Hidekazu Hirano, Saori Mishima, Hiroyuki Takahashi, Tomoyuki Otsuka, Kenta Kawasaki, Takeshi Kawakami, Kazuhiro Yanagihara, Takaya Shimura, Masato Komoda, Kozue Murayama, Keiko Minashi, Yoshiyuki Yamamoto, Yudai Shinohara, Shinichi Nishina, Nobuyuki Musha, Kyoko Kato, Kentaro Kawakami, Katsunori Shinozaki, Kenji Tsuchihashi, Takayuki Ando, Yosuke Kito, Akitaka Makiyama, Seiichiro Mitani, Kaori Hino, Naoki Izawa, Isao Oze, Kei Muro   +29 more
wiley   +1 more source