Results 71 to 80 of about 582,867 (329)

Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer [PDF]

open access: yes, 2013
Background : Preoperative radiotherapy (RT) decreases local recurrence rate and improves survival in stage II and III rectal cancer patients. The combination of chemotherapy with RT has a sound radiobiological rationale, and phase II trials of combined ...
Ceelen, Wim   +2 more
core   +1 more source

Protein Tyrosine Phosphatase 4A1 (PTP4A1) Regulates Early Events in Colorectal Cancer Intraperitoneal Dissemination in the Aged Male Host

open access: yesAging and Cancer, EarlyView.
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang   +17 more
wiley   +1 more source

TAMIS: New Horizons in Modern Colorectal Surgery

open access: yesTurkish Journal of Colorectal Disease
Transanal minimally invasive surgery (TAMIS) has emerged as a major advancement in the management of rectal neoplasms. Building upon the principles of transanal endoscopic microsurgery (TEM), TAMIS provides a cost-effective and more accessible ...
Nurhilal Kızıltoprak   +3 more
doaj   +1 more source

Multiple rectal carcinoids with diffuse ganglioneuromatosis

open access: yesWorld Journal of Surgical Oncology, 2007
Background Rectal carcinoids comprise only about 1% of all anorectal neoplasms. In addition, ganglioneuroma of the gastrointestinal tract is a rare tumor composed ganglion cells, nerve fibers, and supporting cells.
Kosaka Taiichiro   +7 more
doaj   +1 more source

Metachronous liver metastases after long-term follow-up of endoscopic resection for rectal neuroendocrine neoplasms: a report of three cases

open access: yesSurgical Case Reports, 2020
Background Rectal neuroendocrine neoplasms (NENs) are rare, but their incidence has increased in recent years. The metastasis rate is low in cases of a tumor diameter 
Yuma Hane   +13 more
doaj   +1 more source

MRI-detected extramural venous invasion of rectal cancer: Multimodality performance and implications at baseline imaging and after neoadjuvant therapy

open access: yesInsights into Imaging, 2021
MRI is routinely used for rectal cancer staging to evaluate tumor extent and to inform decision-making regarding surgical planning and the need for neoadjuvant and adjuvant therapy.
Akitoshi Inoue   +10 more
doaj   +1 more source

Cancer Risk in Patients With Systemic Sclerosis: A Nationwide Cohort Study in South Korea 2004 to 2021

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na   +4 more
wiley   +1 more source

Habitual intake of flavonoid subclasses and risk of colorectal cancer in two large prospective cohorts [PDF]

open access: yes, 2016
Background: Flavonoids inhibit the growth of colon cancer cells in vitro. In a secondary analysis of a randomized controlled trial, the Polyp Prevention Trial, a higher intake of one sub-class, flavonols, was significantly associated with reduced risk of
Aedín Cassidy   +62 more
core   +1 more source

Lymph node ratio and hematological parameters predict relapse-free survival in Patients With high grade rectal neuroendocrine neoplasms after radical resection: A multicenter prognostic study [PDF]

open access: green, 2023
Xinyu Zeng   +13 more
openalex   +1 more source

Cancer Cells Traverse Faster in Confined Space by Modifying Vimentin filaments With Nuclear Deformation and Promoting the Growth of Desired Tumor Spheroids

open access: yesAdvanced Materials Interfaces, EarlyView.
This study demonstrates how the Vimentin intermediate (VIM) filaments distribution/density regulates the attainment of different migration modes through cytoskeleton rearrangement and controls the nuclear morphology in migrating cells under physical confinement, which facilitates the faster traversing of those cells and the growth of post‐migration ...
Md Kowsar Alam   +4 more
wiley   +1 more source

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