Results 71 to 80 of about 549,282 (362)

Faecal haemoglobin and faecal calprotectin as indicators of bowel disease in patients presenting to primary care with bowel symptoms [PDF]

, 2015
OBJECTIVE: In primary care, assessing which patients with bowel symptoms harbour significant disease (cancer, higher-risk adenoma or IBD) is difficult.
Allison, Allison, Atkin, Callum G Fraser, Castro, Chiang, Craig Mowat, Cubiella, Duffy, Francis A Carey, Fraser, Fraser, Hazazi, Högberg, Jayne Digby, Jellema, Judith A Strachan, Kaul, Kok, Lieberman, McDonald, McDonald, NICE Diagnostics guidance (DG11), Parente, Pavlidis, Rapi, Robert J C Steele, Robyn Wilson, Roseth, Sipponen, Terhaar sive Droste, van Rheenen, Young   +32 more
core   +2 more sources

DMMR status and synchronous lesions predicts metachronous lesions after curative resection for rectal cancer

Frontiers in Surgery
BackgroundThere are no established standard colonoscopy surveillance protocols for patients after curative rectal cancer resection. We investigated the predictive factors for colorectal neoplasms during surveillance colonoscopies to identify patients who
Xijie Chen, Xijie Chen, Xijie Chen, Junguo Chen, Junguo Chen, Junguo Chen, Liang Xu, Liang Xu, Dezheng Lin, Dezheng Lin, Dezheng Lin, Xiaoling Hong, Xiaoling Hong, Xiaoling Hong, Junsheng Peng, Junsheng Peng, Junsheng Peng, Xiaowen He, Xiaowen He, Xiaowen He, Jiancong Hu, Jiancong Hu, Jiancong Hu   +22 more
doaj   +1 more source

Voiding Dysfunction after Total Mesorectal Excision in Rectal Cancer [PDF]

International Neurourology Journal, 2011
Purpose The aim of this study was to assess the voiding dysfunction after rectal cancer surgery with total mesorectal excision (TME). Methods This was part of a prospective study done in the rectal cancer patients who underwent surgery with TME between ...
Jae Heon Kim, Tae Il Noh, Mi Mi Oh, Jae Young Park, Jeong Gu Lee, Jun Won Um, Byung Wook Min, Jae Hyun Bae   +7 more
doaj   +1 more source

Rectal bleeding as a symptom of solitary rectal ulcer syndrome mimicking rectal neoplasm on colonoscopy: A case report

Clinical Case Reports, 2022
Key Clinical MessagePatients complaining of rectal bleeding, constipation, and a suspicious mass in colonoscopy should undergo biopsy. Histological features such as fibromuscular obliteration in the lamina propria favor SRUS, a benign disorder.
Masood Faghih Dinevari, Amirtaher Eftekharsadat, Mahdi Tarverdizadeh, Seyyed Mahdi Rasulimanesh, Ali Riazi, Amirreza Jabbaripour Sarmadian, Samaneh Abbasian   +6 more
openaire   +3 more sources

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]

, 2012
The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J., Plate, Karl H., Scholz, Alexander   +2 more
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Rectal Neoplasm [PDF]

, 2020
openaire   +2 more sources

Endoscopic submucosal dissection vs laparoscopic colorectal resection for early colorectal epithelial neoplasia [PDF]

, 2015
published_or_final_versio
Chiu, PW, Hon, SS, Lee, JF, Leung, WW, Mak, TW, Ng, SS, Wong, CLT   +6 more
core   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

ROLE OF HEREDITARY FACTORS IN THE DEVELOPMENT OF GLIAL BRAIN TUMORS

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Background. The analysis data on the malignant neoplasms incidence among first-degree relatives of probands with glial brain tumors are presented. Goal.
Pashkevich A. M., Antonenkova N. N., Malko M. V.   +2 more
doaj   +1 more source