Results 51 to 60 of about 5,081,991 (350)

Meta-analysis of histopathological outcomes of laparoscopic assisted rectal resection (LARR) vs open rectal resection (ORR) for carcinoma [PDF]

, 2018
BACKGROUND: We conducted a meta-analysis of the randomized evidence to determine the relative merits of histopathological outcomes of laparoscopic assisted (LARR) versus open rectal resection (ORR) for rectal cancer.
Yunus, Rossita Mohamad, Awaiz, Aiman, Awais, Aiaman, Memon, Muhammed Ashraf, Memon, Breda, Khan, Shahjahan   +5 more
core   +1 more source

Incidence and risk factors of permanent stoma after temporary stoma in sphincter-preserving surgery for rectal cancer: a systematic review and Meta-analysis [PDF]

Yixue xinzhi zazhi
Objective To systematically review the incidence and risk factors of permanent stoma after temporary stoma in sphincter-preserving surgery for rectal cancer, and to provide evidence for the formulation of preventive intervention strategies.Methods ...
TAN Yu, PENG Lili, LI Aoqi, XIE Xinwei, XU Liqiong   +4 more
doaj   +1 more source

MRI Tumor Regression Grade and Circulating Tumor DNA as Complementary Tools to Assess Response and Guide Therapy Adaptation in Rectal Cancer

Clinical Cancer Research, 2019
Purpose: Response to preoperative chemo-radiotherapy (CRT) varies. We assessed whether circulating tumor DNA (ctDNA) might be an early indicator of tumor response or progression to guide therapy adaptation in rectal cancer.
S. Khakoo, P. Carter, Gina Brown, N. Valeri, S. Picchia, M. Bali, Ridwan Shaikh, T. Jones, R. Begum, I. Rana, A. Wotherspoon, M. Terlizzo, K. von Loga, E. Kalaitzaki, C. Saffery, D. Watkins, D. Tait, I. Chau, N. Starling, M. Hubank, D. Cunningham   +20 more
semanticscholar   +1 more source

Multicenter, Randomized, Phase III Trial of Short-Term Radiotherapy Plus Chemotherapy Versus Long-Term Chemoradiotherapy in Locally Advanced Rectal Cancer (STELLAR)

Journal of Clinical Oncology, 2022
PURPOSE To ascertain if preoperative short-term radiotherapy followed by chemotherapy is not inferior to a standard schedule of long-term chemoradiotherapy in patients with locally advanced rectal cancer.
Jing Jin, Yuan Tang, Chen Hu, Li-Ming Jiang, Jun Jiang, Ning Li, Wen-Yang Liu, Si-Lin Chen, Shuai Li, N. Lu, Yong Cai, Yong-Heng Li, Yuan Zhu, Guang-Hui Cheng, Hong-Yan Zhang, Xin Wang, Su-Yu Zhu, Jun Wang, Gao-Feng Li, Jia-Lin Yang, Kuan Zhang, Y. Chi, Lin Yang, Hai-Tao Zhou, Ai-Ping Zhou, Shuang-Mei Zou, H. Fang, Shu-Lian Wang, Hai-Zeng Zhang, Xi-Shan Wang, Li-Chun Wei, Wen-Ling Wang, Shixin Liu, Yuan-Hong Gao, Ye-Xiong Li   +34 more
semanticscholar   +1 more source

Malignancy within a Tail Gut Cyst: A Case of Retrorectal Carcinoid Tumour [PDF]

, 2014
Purpose. Tailgut cysts with malignant transformation are rare entities. We discuss the diagnostic strategy and treatment of a malignancy within a tailgut cyst. Methods.
Abukar, AA, Steele, RJC, R. J. C. Steele, P. V. Patil, Abukar, A. A., A. A. Abukar, Patil, P. V., THAHA, MA, C. B. Lim, Lim, C. B., Ramsanahie, A., Carey, F, A. Ramsanahie, M. A. Thaha, Steele, R. J. C., Thaha, M. A., Ramsanahie, A, B. J. Parcell, F. Carey, Lim, CB, Patil, PV, Parcell, B. J.; id_orcid, Carey, F., Parcell, BJ   +23 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Secondary presacral cyst following radical resection for rectal cancer: a case report and literature review

结直肠肛门外科
Presacral cyst is a congenital cystic disease that occurs between the sacrum and the rectum. The main symptoms are sacrococcygeal bulge and defecatory disturbances. It can be diagnosed by imaging examination and has been reported clinically.
Qu Junwang, Liu Shiju, Li Juntan, Wang Hongyan, Xu Wanhai, Luo Gan, Li Tao, Fan Yaoyuan   +7 more
doaj   +1 more source

Transanal endoscopic microsurgery in the treatment of patients with benign neoplasms and early rectal cancer

Сибирский онкологический журнал, 2022
Introduction. Transanal endoscopic microsurgery (tem) is a method that allows the specialists to clearly visualize a tumor and bimanually remove the tumor using a set of special instruments.
V. A. Avdeenko, A. A. Nevolskikh, A. R. Brodsky, R. F. Zibirov, I. A. Orekhov, T. P. Pochuev, Yu. Yu. Mikhaleva, T. P. Berezovskaya, S. A. Myalina, L. O. Petrov, S. A. Ivanov   +10 more
doaj   +1 more source

Approach of Colorectal Surgeons to Lower Rectal Adenocarcinomas: Results from the Turkish Society of Colon and Rectal Surgery Database [PDF]

Aim: This study aimed to analyze surgical preferences and outcomes among patients with lower rectal tumors in Türkiye using data from the national Colorectal Cancer Database of the Turkish Society of Colon and Rectal Surgery (TSCRS).
Mehmet Ali Koç, Kaan Sünter, Turkish Colorectal Cancer Database Study Group, Erman Aytaç, Gülcü, Barış, Eray, İsmail Cem, Okkabaz, Nuri, Özben, Volkan, Bozbıyık, Osman, BİŞGİN, TAYFUN, Rencüzoğulları, Ahmet, Sünter, Kaan, KOÇ, MEHMET ALİ, Işık, Özgen, AYTAÇ, ERMAN   +14 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source