Results 71 to 80 of about 5,081,991 (350)
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Low anterior resection syndrome: Incidence and association with quality of life
Annals of Gastroenterological SurgeryAim Low anterior resection syndrome (LARS) causes devastating symptoms and impairs quality of life (QOL). Although its incidence and risk factors have been reported, these data are scarce in Japan.
Yuko Homma +5 more
doaj +1 more source
Tumor regression and safe distance of distal margin after neoadjuvant therapy for rectal cancer
Frontiers in OncologyNeoadjuvant therapy has been widely employed in the treatment of rectal cancer, demonstrating its utility in reducing tumor volume, downstaging tumors, and improving patient prognosis.
Guilin Yu +4 more
doaj +1 more source
Inflammatory fibroid polyp of rectum mimicking rectal cancer
Kaohsiung Journal of Medical Sciences, 2013 Inflammatory fibroid polyps (IFPs) are rare benign tumors of the rectum. Mutation and activating platelet-derived growth factor receptor alpha (PDGFRA) contribute to tumor development.
Jong-Shiaw Jin +4 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Journal of the Anus, Rectum and Colon, 2021 Pelvic tumor resection with sacrectomy for locally recurrent rectal cancer is a challenging operation with a high complication rate and poor prognosis.
Hiroki Matsui +7 more
doaj +1 more source
Rectal tonsil mimicking a rectal neuroendocrine tumor
Revista Española de Enfermedades DigestivasRectal tonsil is an uncommon reactive lymphoid proliferation that may mimic a rectal neuroendocrine tumor endoscopically and a low-grade lymphoid neoplasm histologically. A 43-year-old woman underwent colonoscopy for abdominal pain, which revealed a smooth, hemispheric subepithelial lesion measuring approximately 22 mm in the lower rectum, 8 cm from ...
Wentao, Wang +2 more
openaire +2 more sources
Cancer Science, 2018 Neoadjuvant therapy for locally advanced rectal cancer is becoming increasingly common. However, biomarkers predicting the response to neoadjuvant therapy have not been established.
Shinji Matsutani +7 more
semanticscholar +1 more source
Histopathologic Evaluation of Neoadjuvant Treatment Response and Tumor Regression Grade
, 2017 Histopathologic response and tumor down-staging after neoadjuvant chemoradiation are major determinants of long term outcome in patients with locoregional rectal cancer. Optimal assessment of histopathologic response requires meticulous gross examination,
Maru, Dipen, Parekh, Dipen, Dipen Maru
core +1 more source
Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer
Arthritis Care &Research, EarlyView.Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman +7 more
wiley +1 more source