Results 81 to 90 of about 438,287 (347)

The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression

open access: yesAdvanced Science, EarlyView.
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu   +5 more
wiley   +1 more source

Ballooning of the rectum [PDF]

open access: yesTransactions of the Royal Academy of Medicine in Ireland, 1892
n ...
openaire   +3 more sources

EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This review provides new perspectives on EGFR's activation, mutations, and their impact on tumor immunotherapy. It summarizes how EGFR is activated and the current EGFR targeting strategy, evaluates their clinical outcomes in combination with immunotherapy, highlighting differential responses in tumors with EGFR wild‐type and different mutants.
Yuanzhuo Gu   +7 more
wiley   +1 more source

Comparison of transcutaneous ultrasound over the right flank with transrectal ultrasonography in the diagnosis of pregnancy in New Zealand dairy herds : a thesis presented in partial fulfillment of the requirements for the degree of Master of Veterinary Science at Massey University [PDF]

open access: yes, 2004
Application of a 3.5 MHz sector transducer over the right flank allows the rapid and clear visualization of bovine pregnancy (ie: fetus, fetal membranes, fetal fluid and/or placentomes).
Glossop, Jaimie Catherine
core  

MRI‐Derived Lymph Nodes Morphological and Topological Structure (LNs‐MTS) Model for Evaluating Immune Status and Prognosis in Rectal Cancer

open access: yesAdvanced Science, EarlyView.
An MRI‐derived Lymph Nodes morphological and topological structure (LNs‐MTS) model is established to evaluate the immune status of the lymph node system in rectal cancer. It provides a non‐invasive, quantitative approach for prognosis assessment and optimizing adjuvant therapy decisions.
Yunxiao Liu   +15 more
wiley   +1 more source

Ileostomy Adenocarcinoma : a case report [PDF]

open access: yes, 2004
Proctocolectomy is the standard treatment for patients suffering from ulcerative colitis which is long-standing, refractory to pharmacotherapy or otherwise associated with complications.
Abela, Joetienne   +2 more
core  

Cancer of the rectum [PDF]

open access: yesTransactions of the Royal Academy of Medicine in Ireland, 1893
n ...
openaire   +3 more sources

Akkermansia muciniphila‐Derived N‐Acetylspermidine Modulates the Localization of Intestinal α1,2‐Fucosylated Proteins to Maintain Gut Homeostasis

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Akkermansia muciniphila alleviates colitis by enhancing intestinal α1,2‐fucosylation through its metabolite N‐acetylspermidine. Mechanistically, N‐acetylspermidine‐induced PIM1 inhibition promotes HDAC2‐mediated reduction of chromatin accessibility at TP73, thereby upregulating C1GALT1C1 to boost α1,2‐fucosylation.
Ye Yao   +10 more
wiley   +1 more source

Minimally Invasive, Bioadaptive Multimodal Sensor Probe with Safe Deployment for Real‐Time Acute Compartment Syndrome Diagnosis

open access: yesAdvanced Science, EarlyView.
A soft, minimally invasive multimodal sensor probe integrates intracompartmental pressure, tissue oxygen saturation, and blood flow sensors into a single platform. By enabling precise measurements and capturing correlations among pressure, oxygenation, and vascular dynamics, the system provides a comprehensive physiological assessment, thereby ...
Seung Gi Seo   +19 more
wiley   +1 more source

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