Results 81 to 90 of about 395,349 (427)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

A rare case of solitary fibrous tumor of the liver and highly differentiated rectal adenocarcinoma

open access: yesИсследования и практика в медицине, 2021
Solitary fibrous tumors (SFT) are rare spindle cell mesenchymal neoplasms of presumably fibroblastic origin with undefined malignancy potential and rare metastasis.
S. A. Shinkarev   +5 more
doaj   +1 more source

The Fröhlich Polaron at Strong Coupling -- Part II: Energy-Momentum Relation and Effective Mass [PDF]

open access: yesarXiv, 2022
We study the Fr\"ohlich polaron model in $\mathbb{R}^3$, and prove a lower bound on its ground state energy as a function of the total momentum. The bound is asymptotically sharp at large coupling. In combination with a corresponding upper bound proved earlier, it shows that the energy is approximately parabolic below the continuum threshold, and that ...
arxiv  

Culture-Independent Evaluation of the Appendix and Rectum Microbiomes in Children with and without Appendicitis

open access: yesPLoS ONE, 2014
Purpose The function of the appendix is largely unknown, but its microbiota likely contributes to function. Alterations in microbiota may contribute to appendicitis, but conventional culture studies have not yielded conclusive information. We conducted a
H. Jackson   +5 more
semanticscholar   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Tumeur stromale à localisation rétro-rectale: entité macroscopique et difficultés chirurgicales

open access: yesThe Pan African Medical Journal, 2018
Les tumeurs stromales gastro-intestinales sont des tumeurs mésenchymateuses peu fréquentes dont la localisation rectale est extrêmement rare, et posent en pré-opératoire un problème de diagnostic et de prise en charge thérapeutique.
Driss Erguibi   +3 more
doaj   +1 more source

Gravitational waves from Extreme Mass Ratio Inspirals in non-pure Kerr spacetimes [PDF]

open access: yes, 2006
To investigate the imprint on the gravitational-wave emission from extreme mass-ratio inspirals in non-pure Kerr spacetimes, we have studied the ``kludge'' waveforms generated in highly-accurate, numerically-generated spacetimes containing a black hole ...
C. W. Misner   +10 more
core   +2 more sources

Sexually transmitted infections of the anus and rectum.

open access: yesWorld Journal of Gastroenterology, 2014
Sexually transmitted infections (STIs) represent a significant public health concern. Several STIs, once thought to be on the verge of extinction, have recently reemerged.
R. Assi   +4 more
semanticscholar   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Colorectal Cancer in Uganda: A 10-Year, Facility-Based, Retrospective Study

open access: yesCancer Management and Research, 2021
Godfrey Wekha,1 Nelson Ssewante,1 Angelique Iradukunda,1 Micheal Jurua,1 Shadia Nalwoga,1 Sharon Lanyero,1 Ronald Olum,1 Felix Bongomin2,3 1School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda; 2Department of Medical ...
Wekha G   +7 more
doaj  

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