Results 81 to 90 of about 1,636,890 (348)

Recurrence and Frequencies

, 2023
Given an infinite word with values in a finite alphabet that admit frequencies for all its factors, the smallest frequency function associates with a given positive integer the smallest frequency for factors of this length, and the recurrence function measures the gaps between successive occurrences of factors.
Berthé, Valérie, Mimouni, Ahmed
openaire   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Local Cancer Recurrence: The Realities, Challenges, and Opportunities for New Therapies

Ca, 2018
Locoregional recurrence negatively impacts both long‐term survival and quality of life for several malignancies. For appropriate‐risk patients with an isolated, resectable, local recurrence, surgery represents the only potentially curative therapy ...
D. Mahvi, Rong Liu, M. Grinstaff, Y. Colson, C. Raut   +4 more
semanticscholar   +1 more source

Recurrent phaeochromocytoma

International Journal of Clinical Practice, 1990
The recurrence of symptoms and hypertension in a patient who has previously undergone an operation for phaeochromocytoma should alert the physician to the need to investigate for recurrent tumour. Failure to perform complete excision of the adrenal gland containing the tumour may lead to disseminated recurrence.
P H, Rowe, R A, Loukota, A, Houghton, W J, Owen, B H, Hicks, I, McColl   +5 more
openaire   +2 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial.

JAMA Surgery, 2019
Importance The patterns of disease recurrence after resection of pancreatic ductal adenocarcinoma with adjuvant chemotherapy remain unclear. Objective To define patterns of recurrence after adjuvant chemotherapy and the association with survival ...
Robert P. Jones, E. Psarelli, R. Jackson, P. Ghaneh, C. Halloran, D. Palmer, F. Campbell, J. Valle, O. Faluyi, D. O’reilly, D. Cunningham, J. Wadsley, S. Darby, T. Meyer, R. Gillmore, A. Anthoney, P. Lind, B. Glimelius, S. Falk, J. Izbicki, G. Middleton, S. Cummins, P. Ross, H. Wasan, A. Mcdonald, T. Crosby, Yu Ting, K. Patel, David Sherriff, R. Soomal, D. Borg, S. Sothi, P. Hammel, M. Lerch, J. Mayerle, C. Tjaden, O. Strobel, T. Hackert, M. Büchler, J. Neoptolemos   +39 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Is Atrial Fibrillation Noninducibility by Burst Pacing After Catheter Ablation Associated With Reduced Clinical Recurrence?A Systematic Review and Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background To date, there is no cumulative evidence supporting the association of atrial fibrillation (AF) noninducibility after ablation and freedom from AF.
Hualong Liu, Ping Yuan, Xin Zhu, Linghua Fu, Kui Hong, Jinzhu Hu   +5 more
doaj   +1 more source

Common surgical procedures in pilonidal sinus disease: A meta-analysis, merged data analysis, and comprehensive study on recurrence

Scientific Reports, 2018
We systematically searched available databases. We reviewed 6,143 studies published from 1833 to 2017. Reports in English, French, German, Italian, and Spanish were considered, as were publications in other languages if definitive treatment and ...
V. Stauffer, M. Luedi, P. Kauf, M. Schmid, M. Diekmann, K. Wieferich, B. Schnüriger, Dietrich Doll   +7 more
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source