Results 81 to 90 of about 1,764,630 (293)

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Predicting recurrence and recurrence-free survival in initially unresectable hepatocellular carcinoma: a novel nomogram for patients undergoing conversion hepatectomy with lenvatinib, PD-1 inhibitor, and interventional therapy

Frontiers in Immunology
PurposeThis research aims to develop prognostic nomograms to predict tumor recurrence and recurrence-free survival (RFS) in individuals with initially unresectable hepatocellular carcinoma (uHCC) who were later subjected to conversion hepatectomy ...
Cheng Xu, Zhihong Tang, Meng Wei, Danxi Liu, Qingqing Pang, Baishan Huang, Xinglin Mo, Feixiang Wu, Feixiang Wu   +8 more
doaj   +1 more source

The Cube Recurrence

, 2004
We construct a combinatorial model that is described by the cube recurrence, a nonlinear recurrence relation introduced by Propp, which generates families of Laurent polynomials indexed by points in $\mathbb{Z}^3$.
Carroll, Gabriel D., Speyer, David E
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

RECURRENT IMMERSIONS

Demonstratio Mathematica, 1999
A submanifold \(f: M^m \to \mathbb{R}^{m+d}\) is said to have pointwise \(k\)-planar normal section (P\(k\)-PNS) if, for each normal section \(\gamma\), the set \(\{\gamma'(0), \gamma''(0), {\cdots} , \gamma^{(k+1)}(0) \}\) is linearly dependent. Such an \(M\) is called proper (\(\text{PP}k\text{-PNS}\) if it is not P(\(k-1\))-PNS [\textit{B.-Y.
Arslan, Kadri, Deszcz, Ryszard, Murathan, Cengizhan, Özgür, Cihan   +3 more
openaire   +4 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

p-Numerical Semigroups of Triples from the Three-Term Recurrence Relations

Axioms
Many people, including Horadam, have studied the numbers Wn, satisfying the recurrence relation Wn=uWn−1+vWn−2 (n≥2) with W0=0 and W1=1. In this paper, we study the p-numerical semigroups of the triple (Wi,Wi+2,Wi+k) for integers i,k(≥3).
Jiaxin Mu, Takao Komatsu
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Epigenetic Characteristics in Primary and Recurrent Glioblastoma—Influence on the Clinical Course

Biomedicines
Objective: Epigenetic tumor characteristics are in focus for glioblastoma prognosis. This raises the question if these characteristics present with stable expression during the progression of the disease, and if potential temporal instability might ...
Alexander Quiring, Hannah Spielmann, Fritz Teping, Safwan Saffour, Fatemeh Khafaji, Walter Schulz-Schaeffer, Nathan Monfroy, Joachim Oertel, Stefan Linsler, Christoph Sippl   +9 more
doaj   +1 more source