Results 51 to 60 of about 93,434 (284)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Detection of Causal Relations in Time Series Affected by Noise in Tokamaks Using Geodesic Distance on Gaussian Manifolds

Entropy, 2017
: Modern experiments in Magnetic Confinement Nuclear Fusion can produce Gigabytes of data, mainly in form of time series. The acquired signals, composing massive databases, are typically affected by significant levels of noise.
Andrea Murari, Teddy Craciunescu, Emmanuele Peluso, Michela Gelfusa, JET Contributors   +4 more
doaj   +1 more source

Cross recurrence plots.

, 2015
Cross recurrence plots of sample data for each of four conditions. Left-top, two-finger in-phase condition; Right-top, two-finger anti-phase condition; Left-bottom, four-finger in-phase condition; Right-bottom, four-finger anti-phase condition.
Kentaro Kodama (754145), Nobuhiro Furuyama (754146), Tetsunari Inamura (754147)   +2 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The Application of Recurrence Plots to Identify Nonlinear Responses Using Magnetometer Data for Wind Turbine Design

Machines
This work uses recurrence plots (RPs) to identify nonlinearities and non-stationary conditions in wind turbines. Traditionally, recurrence plots have been applied to vibration or acoustic data; this paper applies them to magnetometer and accelerometer ...
Juan Carlos Jauregui-Correa, Luis Morales-Velazquez   +1 more
doaj   +1 more source

Detection of Spatio-Temporal Recurrent Patterns in Dynamical Systems

Frontiers in Applied Mathematics and Statistics, 2019
Background: The study of repetitive (quasi-periodic) spatio-temporal patterns in complex dynamical systems with a well defined spatial structure may be complicated if the recurrent behavior is confined to specific local regions, where it lasts for a ...
Pietro Bonizzi, Ralf Peeters, Stef Zeemering, Arne van Hunnik, Olivier Meste, Joël Karel   +5 more
doaj   +1 more source

Recurrence Plots from Altimetry Data of Some Lakes in Africa [PDF]

, 2014
The paper shows recurrence plots obtained from time series of the level variations of four lakes in Africa (Nasser, Tana, Chad and Kainji). The data, coming from remote sensing, are provided by the United States Department of Agriculture.
Sparavigna, Amelia Carolina, Carolina Sparavigna, Amelia   +1 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Generalised recurrence plot analysis for spatial data

Physics Letters A, 2007
Recurrence plot based methods are highly efficient and widely accepted tools for the investigation of time series or one-dimensional data. We present an extension of the recurrence plots and their quantifications in order to study recurrent structures in higher-dimensional spatial data. The capability of this extension is illustrated on prototypical 2D
Marwan, N., Kurths, J., Saparin, P.
openaire   +3 more sources