Results 151 to 160 of about 162,152 (315)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Recurrence of gastropathies caused by administration of nonsteroid anti-inflammatory drugs
Терапевтический архив, 2003 Aim. To estimate frequency of ulcers and erosions associated with administration of nonsteroid antiinflammatory drugs (NSAID) in patients with rheumatic diseases. Material and methods.
A Е Karateev
doaj
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Journal of Neurology, Neurosurgery & Psychiatry, 2001 A, Petzold, G T, Plant
openaire +2 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Recurrences and graphs of recurrences
U prvom dijelu rada prebrojavamo popločenja uskih traka šesterokutne mreže s unaprijed poznatim brojem pločica određenog tipa i istražujemo mogućnost dobivanja identiteta o nizovima koje tako dobivamo. Preciznije, istražujemo na koliko se načina može popločati uska šesterokutna mreža koristeći samo monomere i dimere, a s unaprijed određenim brojem ...
openaire +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Combinatorial recurrences and linear difference equations
In this work we introduce the triangular arrays of depth greater than 1 given by linear recurrences, that generalize some well known recurrences that appear in enumerative combinatorics.
Encinas Bachiller, Andrés Marcos +1 more
core +1 more source