Results 51 to 60 of about 717,209 (287)

Recurrent airway obstruction in horses - an allergic inflammation: a review

Veterinární Medicína, 2011
Recurrent airway obstruction (RAO), also known as heaves, is a debilitating and incurable disease of the equine airway. Affected horses develop bronchoconstriction and neutrophilic airway inflammation as a result of exposure to specific airborne ...
G. Moran, H. Folch
doaj   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Increased hypoxia-inducible factor 1α expression in lung cells of horses with recurrent airway obstruction

BMC Veterinary Research, 2012
Background Recurrent airway obstruction (RAO, also known as equine heaves) is an inflammatory condition caused by exposure of susceptible horses to organic dusts in hay.
Toussaint Marie, Fievez Laurence, Desmet Christophe J, Pirottin Dimitri, Farnir Frédéric, Bureau Fabrice, Lekeux Pierre   +6 more
doaj   +1 more source

Association of wheezing phenotypes with fractional exhaled nitric oxide in children [PDF]

Korean Journal of Pediatrics, 2014
Asthma comprises a heterogeneous group of disorders characterized by airway inflammation, airway obstruction, and airway hyperresponsiveness (AHR). Airway inflammation, which induces AHR and recurrence of asthma, is the main pathophysiology of asthma ...
Jung Yeon Shim
doaj   +1 more source

Airway Mucus in Recurrent Airway Obstruction—Short-Term Response to Environmental Challenge

Journal of Veterinary Internal Medicine, 2004
Abstract Mucus accumulation and neutrophilic inflammation in the airways are hallmarks of heaves. Endoscopically visible mucus accumulations, however, have not been studied during exposure to dusty hay and allergens (ie, environmental challenge).
V, Gerber, A, Lindberg, C, Berney, N E, Robinson   +3 more
openaire   +2 more sources

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Effects of soaked hay on lung function and airway inflammation in horses with severe asthma

Journal of Veterinary Internal Medicine
Background Reducing inhaled dust particles improves lung function in horses with severe asthma. Soaked hay is commonly used by owners, but its efficacy in improving lung function and inflammation has not been documented. Objectives To measure the effects
Roxane Westerfeld, Flavie Payette, Valérie Dubuc, Estelle Manguin, Khristine Picotte, Guy Beauchamp, Christian Bédard, Mathilde Leclere   +7 more
doaj   +1 more source

Tracheobronchomalacia

Journal of the Belgian Society of Radiology, 2011
Background: A 51-year-old female patient was referred for a high-resolution CT scan of the lungs, to screen for bronchiectasis and infection. She had a long medical history starting with right sided breast cancer (pT2N0M0) in 1993 for which she was ...
P A de Jong, M G Lam
doaj   +1 more source

Equine Asthma: Current Understanding and Future Directions

Frontiers in Veterinary Science, 2020
The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the latest information on Equine Asthma and provide future research directions. Current clinical and molecular asthma phenotypes and endotypes in humans were discussed and
Laurent Couetil, Jacqueline M. Cardwell, Renaud Leguillette, Melissa Mazan, Eric Richard, Dorothee Bienzle, Michela Bullone, Vinzenz Gerber, Kathleen Ivester, Jean-Pierre Lavoie, James Martin, Gabriel Moran, Artur Niedźwiedź, Nicola Pusterla, Cyprianna Swiderski   +14 more
doaj   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source