Results 71 to 80 of about 695,468 (282)
Augmenting flexibility: mutual inhibition between inhibitory neurons expands functional diversity
iScienceSummary: Recent advances in microcircuit analysis of nervous systems have revealed a plethora of mutual connections between inhibitory interneurons across many different species and brain regions.
Belle Liu +2 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
On associated homogeneous Gelfand functions
St. Petersburg Polytechnical University Journal: Physics and MathematicsThe paper proposes refined definitions for associated homogeneous functions (AHFs) of real variables, which are of great practical importance for a wide range of problems. I. M. Gelfand and Z. Ya.
Berdnikov Alexander +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Bifurcation in a Discrete-Time Piecewise Constant Dynamical System
Discrete Dynamics in Nature and Society, 2013 The study of recurrent neural networks with piecewise constant transition or control functions has attracted much attention recently because they can be used to simulate many physical phenomena.
Chenmin Hou, Sui Sun Cheng
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Modeling Belt-Servomechanism by Chebyshev Functional Recurrent Neuro-Fuzzy Network
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2008 A novel Chebyshev functional recurrent neuro-fuzzy (CFRNF) network is developed from a combination of the Takagi-Sugeno-Kang (TSK) fuzzy model and the Chebyshev recurrent neural network (CRNN).
Yuan-Ruey HUANG +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Distinctive Lexical Patterns in Russian Patient Information Leaflets: A Corpus-Driven Study
Russian journal of linguistics: Vestnik RUDN, 2019 This methodologically-oriented corpus-driven study focuses on distinctive patterns of language use in a specialized text type, namely Russian patient information leaflets.
Łukasz Grabowski
doaj +1 more source
Attractors in spacetimes and time functions
, 2016 We develop a new approach to the existence of time functions on Lorentzian manifolds, based on Conley's work regarding Lyapunov functions for dynamical systems.
Monclair, Daniel
core