Results 21 to 30 of about 797,428 (374)

Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage

Frontiers in Immunology, 2021
An appropriate development of the placenta consisting of trophoblast cell migration, invasion, proliferation, and apoptosis, is essential to establishing and maintaining a successful pregnancy.
Jiayu Wang, Jinli Ding, Sainan Zhang, Xin Chen, Si-si Yan, Yan Zhang, Tailang Yin   +6 more
semanticscholar   +1 more source

Dysfunction of Shh signaling activates autophagy to inhibit trophoblast motility in recurrent miscarriage

Experimental and Molecular Medicine, 2021
In early pregnancy, the placenta anchors the conceptus and supports embryonic development and survival. This study aimed to investigate the underlying functions of Shh signaling in recurrent miscarriage (RM), a serious disorder of pregnancy.
Yibin Pan, Lili Yan, Qiaoqiao Chen, Cheng Wei, Y. Dai, X. Tong, Haiyan Zhu, Meifei Lu, Yanling Zhang, Xiao-ying Jin, Tai Zhang, Xiaona Lin, F. Zhou, Songying Zhang   +13 more
semanticscholar   +1 more source

Immunotherapy for recurrent miscarriage [PDF]

Cochrane Database of Systematic Reviews, 2006
Because immunological aberrations might be the cause of miscarriage in some women, several immunotherapies have been used to treat women with otherwise unexplained recurrent pregnancy loss.The objective of this review was to assess the effects of any immunotherapy, including paternal leukocyte immunization and intravenous immune globulin on the live ...
T. Flint Porter, Luchin F Wong, James R. Scott   +2 more
openaire   +4 more sources

Down‐regulation of the Sp1 transcription factor by an increase of microRNA-4497 in human placenta is associated with early recurrent miscarriage

Reproductive Biology and Endocrinology, 2021
Background The pathophysiological mechanism of recurrent miscarriage (RM) is unclear. The goals of this study were to determine the role of microRNA-4497 overexpression in placental villus tissues in early RM; To identify the potential target mRNAs of ...
Huaiyun Tang, Linqing Pan, Yun Xiong, Leilei Wang, Yugui Cui, Jiayin Liu, LiSha Tang   +6 more
semanticscholar   +1 more source

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities [PDF]

, 2015
Background : Observational studies suggest higher pregnancy rates after the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions, which are detectable in 10% to 15% of women seeking treatment for ...
Bosteels, Jan, Broekmans, Frank J, D'Hooghe, Thomas M, Kasius, Jenneke, Mol, Ben Willem J, Weyers, Steven   +5 more
core   +9 more sources

A hidden cause of infertility in hypothyroid patients [PDF]

, 2020
Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists ...
Ahmed, Soha Magdy, Allam, Magdy Mohamed, Barakat, Sherine Samir, El-Zawawy, Hanaa Tarek, Saleh, Rasha Noureldin M.   +4 more
core   +1 more source

Effect of Happiness Counseling on Depression, Anxiety, and Stress in Women with Recurrent Miscarriage

International Journal of Women's Health, 2021
Purpose This study investigated the effectiveness of a happiness counseling program on depression, anxiety, and stress in pregnant women with a history of recurrent miscarriage.
N. B. Elsharkawy, S. Mohamed, M. H. Awad, M. M. Ouda   +3 more
semanticscholar   +1 more source

Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells : a randomised, double-blind placebo-controlled feasibility trial [PDF]

, 2020
Background: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury.
Brighton, Paul (Paul J.), Brosens, Jan J., Da Costa, Maria José Minhoto Diniz, Ewington, Lauren J., Fishwick, Katherine, Fujihara, Risa, Kimani, Peter K., Lacey, Lauren, Lucas, Emma S., Muter, Joanne, Polanco, Angela, Quenby, Siobhan, Takeda, Satoru, Tewary, Shreeya   +13 more
core   +1 more source

‘An extra level of kind of torment’: Views and experiences of recurrent miscarriage care during the initial phases of COVID‐19 in Ireland—A qualitative interview study

Health Expectations, 2023
Introduction Maternity services underwent much change during the COVID‐19 pandemic. Research on the impact on miscarriage care and experiences during this time is sparse.
Rebecca Dennehy, Marita Hennessy, Jennifer Ui Dhubhgain, Con Lucey, Keelin O′Donoghue   +4 more
doaj   +1 more source

Recurrent pregnancy loss is associated with a pro-senescent decidual response during the peri-implantation window [PDF]

, 2020
During the implantation window, the endometrium becomes poised to transition to a pregnant state, a process driven by differentiation of stromal cells into decidual cells (DC).
Brighton, Paul (Paul J.), Brosens, Jan J., Diniz-da-Costa, Maria, Ewington, Lauren J., Fishwick, Katherine J., Kong, Chow-Seng, Lipecki, Julia, Lucas, Emma S., Muter, Joanne, Odendaal, Joshua, Ott, Sascha, Quenby, Siobhan, Vrljicak, Pavle   +12 more
core   +1 more source