Results 101 to 110 of about 4,179 (318)

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

Novae: An Important Source of Lithium in the Galaxy

open access: yesThe Astrophysical Journal
The source of the Galactic lithium (Li) has long been a puzzle. With the discovery of Li in novae, extensive research has been conducted. However, there still exists a significant disparity between the observed abundance of Li in novae and the existing ...
Jun Gao   +6 more
doaj   +1 more source

Early Super Soft Source Spectra in RS Oph

open access: yesActa Polytechnica CTU Proceedings, 2015
Recent Swift X-ray monitoring campaigns of novae have revealed extreme levels of variability during the early super-softsource (SSS) phase. The first time this was observed was during the 2006 outburst of the recurrent nova RS Oph which was also ...
J.-U. Ness
doaj   +1 more source

RS Ophiuchi: Thermonuclear Explosion or Disc Instability?

open access: yes, 2009
Sokoloski et al (2008) have recently reported evidence that the recurrent nova RS Ophiuchi produced a pair of highly collimated radio jets within days of its 2006 outburst. This suggests that an accretion disc must be present during the outburst. However
A. R. King   +24 more
core   +2 more sources

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

Hydrodynamic Simulations of Oxygen–Neon Classical Novae as Galactic 7Li Producers and Potential Accretion-induced Collapse Progenitors

open access: yesThe Astrophysical Journal
We report on studies of classical nova (CN) explosions where we follow the evolution of thermonuclear runaways (TNRs) on oxygen–neon (ONe) white dwarfs (WDs).
Sumner Starrfield   +5 more
doaj   +1 more source

Orbital periods of recurrent novae

open access: yesThe Astrophysical Journal, 1990
The class of recurrent novae (RN) with thermonuclear runaways contains only three systems (T Pyx, U Sco, and V394 CrA), for which no orbital periods are known. This paper presents a series of photometric observations where the orbital periods for all three systems are discovered.
openaire   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan   +11 more
wiley   +1 more source

Challenging Classical Paradigms: Recurrent Nova M31N 2017-01e, a BeWD System in M31?

open access: yesThe Astrophysical Journal
M31N 2017-01e is the second-fastest recurrent nova known, with a recurrence period of 2.5 yr in the Andromeda galaxy (M31). This system exhibits a unique combination of properties: a low outburst amplitude (∼3 mag), starkly contrasting with known ...
Shatakshi Chamoli   +5 more
doaj   +1 more source

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