Results 141 to 150 of about 2,028,352 (356)

Red blood cell storage duration is not associated with clinical outcomes for acute chest syndrome in children with sickle cell disease

, 2015
Melanie E. Fields, Monica L. Hulbert, Ling Chen, Ari N. Berlin, Ron Jackups, Philip C. Spinella   +5 more
openalex   +2 more sources

Comparative Rheology of Human and Trout Red Blood Cells [PDF]

, 1993
Gerard B. Nash, Stuart Egginton
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

KLRG1 re-defines a leukemic clone of CD8 effector T cells sensitive to PI3K inhibitor in T cell large granular lymphocytic leukemia

Cell Reports Medicine
Summary: T cell large granular lymphocytic leukemia (T-LGLL) is a clonal lymphoproliferative disorder, originated from mature effector memory CD8+ T cells. It is a challenge to define the leukemic T cell clones due to the lack of definite markers.
Lele Zhang, Chen Qiu, Ruonan Li, Yucan Shen, Linzhu Tian, Hong Chang, Qian Liang, Hong Pan, Zhen Gao, Weiwang Li, Jingyu Zhao, Liwei Fang, Xiao Yu, Jing Xu, Zhexiang Kuang, Weiping Yuan, Yajing Chu, Jun Shi   +17 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Machine Learning‐Based Detection of HbS and HbC Carriers in the UK General Population

eJHaem
Background Haemoglobin S (HbS) and C (HbC) are the most important sickling variants on the African continent, imposing major health burdens. Early detection of carrier status is crucial but often hindered by resource limitations.
Frederik Christensen, Deniz Kenan Kılıç, Alexander Djupnes Fuglkjær, Jesper Petersen, Tarec Christoffer El‐Galaly, Andreas Glenthøj, Jens Helby, Izabela Ewa Nielsen   +7 more
doaj   +1 more source

Role of hemoglobin oxygenation in the modulation of red blood cell mechanical properties by nitric oxide

, 2009
Mehmet Üyüklü, Herbert J. Meiselman, Oğuz K. Başkurt   +2 more
openalex   +1 more source

Correlation between GEM Premier 3000 and Vitros5.1+5600, SYSMEX XN-9000 in Detecting Electrolytes and Red Blood Cell Volume

, 2022
Weihua Xue, Shunling Li
openalex   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source