Results 21 to 30 of about 2,028,352 (356)

Consensus on Complement Inhibitor Therapy and Management of Paroxysmal Nocturnal Hemoglobinuria

罕见病研究
Paroxysmal nocturnal hemoglobinuria (PNH), a rare clonal disease of hematopoietic stem cells caused by mutations in the phosphatidylinositol N-acetylglucosaminyltransferase subunit A (PIGA) gene, may lead to the deficiency of glycosylated ...
Red Blood Cell Disease (Anemia) Group, Chinese Society of Hematology, Chinese Medical Association
doaj   +1 more source

Effects of a Maximal Exercise Followed by a Submaximal Exercise Performed in Normobaric Hypoxia (2500 m), on Blood Rheology, Red Blood Cell Senescence, and Coagulation in Well-Trained Cyclists

Metabolites, 2023
Acute normoxic exercise impacts the rheological properties of red blood cells (RBC) and their senescence state; however, there is a lack of data on the effects of exercise performed in hypoxia on RBC properties.
Romain Carin, Gabriel Deglicourt, Hamdi Rezigue, Marie Martin, Christophe Nougier, Camille Boisson, Yesim Dargaud, Philippe Joly, Céline Renoux, Philippe Connes, Emeric Stauffer, Elie Nader   +11 more
doaj   +1 more source

Force balance and membrane shedding at the Red Blood Cell surface

, 2006
During the aging of the red-blood cell, or under conditions of extreme echinocytosis, membrane is shed from the cell plasma membrane in the form of nano-vesicles.
D. E. Discher, J. M. Werre, L. Backman, N. G. Van Kampen, Nir Gov, Pierre Sens, R. Bucki, R. E. Waugh, S. Levin, S.-C. Liu, S. P. Sutera, V. Bennett, W. H. Reinhart, Z. Tochner   +13 more
core   +1 more source

Leukocyte margination in alveolar capillaries: Interrelationship with functional capillary geometry and microhemodynamics [PDF]

, 1999
The pulmonary capillary microvasculature harbors a large pool of intravascularly marginated leukocytes. In this study, we investigated the interrelationship of leukocyte margination with characteristics of functional capillary geometry and ...
Goetz, Alwin Eduard, Kuebler, Wolfgang M., Kuhnle, Gerhard E. H.   +2 more
core   +1 more source

Aging Markers in Equine Red Blood Cells

Frontiers in Physiology, 2019
Detection of hematopoietic activity in horses is a challenge due to the lack of cells carrying reticulocyte markers such as RNA remnants or CD71 in the circulation.
Sandra Kämpf, Sandra Kämpf, Elena Seiler, Jolanta Bujok, Jolanta Bujok, Regina Hofmann-Lehmann, Barbara Riond, Asya Makhro, Anna Bogdanova, Anna Bogdanova   +9 more
doaj   +1 more source

Neonatal red blood cell transfusion [PDF]

Vox Sanguinis, 2020
Transfusions are more common in premature infants with approximately 40% of low birth weight infants and up to 90% of extremely low birth weight infants requiring red blood cell transfusion. Although red blood cell transfusion can be life‐saving in these preterm infants, it has been associated with higher rates of complications including necrotizing ...
Andréanne, Villeneuve, Valérie, Arsenault, Jacques, Lacroix, Marisa, Tucci   +3 more
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Automated and closed clinical-grade manufacturing protocol produces potent NK cells against neuroblastoma cells and AML blasts

Scientific Reports
Natural killer (NK) cells are a promising allogeneic immunotherapy option due to their natural ability to kill tumor cells, and due to their apparent safety.
Farhana Jahan, Leena Penna, Annu Luostarinen, Laurens Veltman, Heidi Hongisto, Kaarina Lähteenmäki, Sabine Müller, Seppo Ylä-Herttuala, Matti Korhonen, Kim Vettenranta, Anita Laitinen, Urpu Salmenniemi, Erja Kerkelä   +12 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Assessment of vitamin E status in patients with systemic inflammatory response syndrome: plasma, plasma corrected for lipids or red blood cell measurements? [PDF]

, 2009
<b>Background:</b> There is some evidence that the plasma vitamin E status is perturbed as part of systemic inflammatory response and correcting this with other plasma markers may not lead to reliable results.
Duncan, A., Kinsella, J., Leivaditi, D., McMillan, D.C., O'Reilly, D.S., Talwar, D., Vasilaki, A.T.   +6 more
core   +1 more source