Results 61 to 70 of about 131,636 (249)

Rouleaux formation of white blood cells and platelets in leukemia

Bioscience Journal, 2018
The objective of this study was to measure the effects of glucose and salt level on white blood cells, red blood cells and platelets (PLTs) in the blood of a leukemic patient by using a white light microscope.
Hafeez Ullah, Khalid Naeem, Munir Akhtar, Fayyaz Hussain, Mukhtar Ahmad   +4 more
doaj   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The influence of in vitro aggregation of apheresis platelets on their quality

Zhongguo shuxue zazhi
[Objective] To study the impact of disaggregation on the quality of in vitro aggregated apheresis platelets. [Methods] The apheresis platelets collected from Guangzhou Blood Center served as the study samples.
LIU Huizhong, LI Huaheng, CHEN Dawei, OU Daixiao, ZHONG Huibin, ZHANG Yue, LIANG Huaqin   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Higher Daily Physical Activity Level Is Associated with Lower RBC Aggregation in Carotid Artery Disease Patients at High Risk of Stroke

Frontiers in Physiology, 2017
Aim: Carotid artery disease (CAD) is an atherosclerotic inflammatory disease that affects the arterial wall, specifically at points of bifurcation where blood flow is disturbed. Abnormal blood rheology could participate in the pathophysiology of ischemic
Pauline Mury, Pauline Mury, Camille Faes, Camille Faes, Antoine Millon, Antoine Millon, Mathilde Mura, Mathilde Mura, Céline Renoux, Céline Renoux, Céline Renoux, Sarah Skinner, Sarah Skinner, Virginie Nicaise, Philippe Joly, Philippe Joly, Philippe Joly, Nellie Della Schiava, Patrick Lermusiaux, Philippe Connes, Philippe Connes, Philippe Connes, Vincent Pialoux, Vincent Pialoux, Vincent Pialoux   +24 more
doaj   +1 more source

Hemorheological Alterations in Patients with Heart Failure with Reduced Ejection Fraction Treated by Resveratrol

Cardiovascular Therapeutics, 2020
Objectives. Several beneficial effects of resveratrol have already been published. This study evaluated the effect of resveratrol on the hemorheological parameters in patients with heart failure with reduced ejection fraction. Methods.
Roland Gal, Dora Praksch, Peter Kenyeres, Miklos Rabai, Kalman Toth, Robert Halmosi, Tamas Habon   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Plasma Viscosity : A Risk Factor In Hypertension

Indian Journal of Community Medicine, 1989
Haemorrheological study on hypertension was done at Indian Institute of Technology Hospital, Bombay. Male population in the age groups of 35 to 60 years was screened for hypertension from February 1986 to February 1987.
Puniyani R. R, Khobragade Y. S, Jaiswal V. S   +2 more
doaj  

Protective Effect of Total Flavonoids of Seabuckthorn (Hippophae rhamnoides) in Simulated High-Altitude Polycythemia in Rats

Molecules, 2012
Seabuckthorn (Hippophae rhamnoides L.) has been used to treat high altitude diseases. The effects of five-week treatment with total flavonoids of seabuckthorn (35, 70, 140 mg/kg, ig) on cobalt chloride (5.5 mg/kg, ip)- and hypobaric chamber (simulating 5,
Sheng-Ya Zeng, Shi-Wen Zhou, Xiao-Huang Du, Ji-Yin Zhou   +3 more
doaj   +1 more source