Transfusion of older red blood cell units, cytokine burst and alloimmunization: a case-control study [PDF]
BACKGROUND: Experimental data have shown that the transfusion of older red blood cell units causes alloimmunization, but the clinical applicability of this statement has never been properly assessed in non-sickle cell patients.
Carla Luana Dinardo +4 more
doaj +2 more sources
Reticulocytes in donor blood units enhance red blood cell alloimmunization [PDF]
Although red blood cell (RBC) transfusions save lives, some patients develop clinically-significant alloantibodies against donor blood group antigens, which then have adverse effects in multiple clinical settings. Few effective measures exist to prevent
Tiffany A. Thomas +12 more
doaj +2 more sources
Red cell transfusion and alloimmunization in sickle cell disease [PDF]
Red cell transfusion remains a critical component of care for acute and chronic complications of sickle cell disease. Randomized clinical trials demonstrated the benefits of transfusion therapy for prevention of primary and secondary strokes and ...
Grace E. Linder, Stella T. Chou
doaj +2 more sources
Red blood cell and leukocyte alloimmunization in patients awaiting kidney transplantation
Objective: To determine the rates of red blood cell and leukocyte alloimmunization in patients with chronic kidney disease awaiting kidney transplantation. Methods:
Silvia Fernandes Ribeiro da Silva +6 more
doaj +2 more sources
Red Cell Alloimmunization Among Transfused Chronic Kidney Disease Patients: A Hospital-Based Study in Southwestern Uganda [PDF]
Elizabeth A John,1 Enoch Muwanguzi,1 Robert Wagubi,1 Simon Peter Rugera,1 Charles Nkubi Bagenda,1 Rose Muhindo,2 Benson Okongo1 1Department of Medical Laboratory Science, Mbarara University of Science and Technology, Mbarara City, Uganda; 2Department of ...
John EA +6 more
doaj +1 more source
Red cell alloimmunization is associated with development of autoantibodies and increased red cell transfusion requirements in myelodysplastic syndrome [PDF]
Up to 90% of patients with a myelodysplastic syndrome require red blood cell transfusion; nevertheless, comprehensive data on red cell alloimmunization in such patients are limited.
Deepak Singhal +16 more
doaj +2 more sources
Red blood cell alloimmunization is influenced by the delay between Toll-like receptor agonist injection and transfusion [PDF]
Murine models of red blood cell transfusion show that inflammation associated with viruses or methylated DNA promotes red blood cell alloimmunization.
Rahma Elayeb +4 more
doaj +2 more sources
Study of red blood cell alloimmunization in multitransfused thalassemic children of Jammu region
Introduction: Thalassemia is one of the most common genetic disorder of hemoglobin synthesis in Jammu region. Although RBC transfusion is life saving for these patients, it may be associated with some complications like RBC alloimmunization.
Ashu Dogra +3 more
doaj +2 more sources
Red cell alloimmunization in multitransfused hepatobiliary patients at hospital Selayang
BACKGROUND: Transfusion support is vital for the management of patients with hepatobiliary disease. Repeated blood transfusions increase the risk of alloimmunization, i.e., the development of alloantibodies, which might lead to difficulties in blood ...
Prasanthini Nahendran +5 more
doaj +2 more sources
Characterization of circulating and cultured Tfh-like cells in sickle cell disease in relation to red blood cell alloimmunization status. [PDF]
Balbuena-Merle R +9 more
europepmc +2 more sources

